儿童残疾的感染性病因：孟加拉国农村一项试点研究的结果
Infectious causes of childhood disability: results from a pilot study in rural Bangladesh.
作者信息
Khandaker Gulam, Muhit Mohammad, Rashid Harunor, Khan Aynul, Islam Johurul, Jones Cheryl, Booy Robert
机构信息
National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases, Sydney, NSW 2145, Australia The Discipline of Paediatrics and Child Health, The University of Sydney, Sydney, NSW 2145, Australia The Marie Bashir Institute for Emerging Infections and Biosecurity (MBI), Sydney Medical School, The University of Sydney, Sydney, NSW 2145, Australia
Child Sight Foundation (CSF), Dhaka 1213, Bangladesh Faculty of Public Health and Life Sciences, University of South Asia, Dhaka 1213, Bangladesh.
出版信息
J Trop Pediatr. 2014 Oct;60(5):363-9. doi: 10.1093/tropej/fmu031. Epub 2014 Jun 13.
PURPOSE
To identify the contribution of infectious aetiologies to major childhood disabilities in Bangladesh.
METHODS
Active community-based survey was conducted for severe childhood disability using the Key Informants Method between September 2011 and March 2012 in a rural sub-district of Bangladesh.
RESULTS
We screened 1069 children and identified 859 with severe disabilities. The mean age of the disabled children was 8.5 year and 42.9% were girls. The major forms of impairments/conditions were cerebral palsy (n = 324, 37.7%), hearing impairment (n = 201, 23.4%), physical impairment (n = 147, 17.1%), visual impairment (n = 49, 5.7%), cerebral palsy with epilepsy (n = 39, 4.5%) and epilepsy (n = 41, 4.7%). Congenital rubella syndrome was identified in 1.1% (n = 9). 7.1% disabilities resulted from clinically confirmed infections, and another 10.8% originated from probable infections; thus a total of 17.9% disabilities were related to an infectious origin.
CONCLUSIONS
Infectious diseases appear to be one of the major causes of severe childhood disability in rural Bangladesh.
目的
确定感染性病因对孟加拉国儿童主要残疾问题的影响。
方法
2011年9月至2012年3月期间，在孟加拉国一个农村分区采用关键信息提供者法开展了基于社区的儿童严重残疾主动调查。
结果
我们筛查了1069名儿童，确定其中859名有严重残疾。残疾儿童的平均年龄为8.5岁，女孩占42.9%。主要的损伤/病症形式为脑瘫（n = 324，37.7%）、听力障碍（n = 201，23.4%）、身体损伤（n = 147，17.1%）、视力障碍（n = 49，5.7%）、伴有癫痫的脑瘫（n = 39，4.5%）和癫痫（n = 41，4.7%）。先天性风疹综合征的确诊率为1.1%（n = 9）。7.1%的残疾由临床确诊感染导致，另有10.8%源于可能的感染；因此，总计17.9%的残疾与感染源有关。
结论
在孟加拉国农村地区，传染病似乎是儿童严重残疾的主要原因之一。
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