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利用电子直线加速器束流光生产(99)钼/(99m)锝

Photo-production of (99)Mo/(99m)Tc with electron linear accelerator beam.

作者信息

Avagyan R, Avetisyan A, Kerobyan I, Dallakyan R

机构信息

A. I. Alikhanyan National Science Laboratory (Yerevan Physics Institute) Foundation, Yerevan, Armenia.

出版信息

Nucl Med Biol. 2014 Sep;41(8):705-9. doi: 10.1016/j.nucmedbio.2014.04.132. Epub 2014 May 9.

Abstract

We report on the development of a relatively new method for the production of (99)Mo/(99m)Tc. The method involves the irradiation of natural molybdenum using high-intensity bremsstrahlung photons from the electron beam of the LUE50 linear electron accelerator located at the Yerevan Physics Institute (YerPhi). The production method has been developed and shown to be successful. The linear electron accelerator at YerPhi was upgraded to allow for significant increases of the beam intensity and spatial density. The LUE50 was also instrumented by a remote control system for ease of operation. We have developed and tested the (99m)Tc extraction from the irradiation of natural MoO3. This paper reports on the optimal conditions of our method of (99)Mo production. We show the success of this method with the production and separation of the first usable amounts of (99m)Tc.

摘要

我们报告了一种相对较新的生产(99)钼/(99m)锝的方法的进展情况。该方法包括使用位于埃里温物理研究所(YerPhi)的LUE50线性电子加速器的电子束产生的高强度轫致辐射光子照射天然钼。这种生产方法已经开发出来并证明是成功的。YerPhi的线性电子加速器进行了升级,以使束流强度和空间密度显著提高。LUE50还配备了遥控系统以便于操作。我们已经开发并测试了从天然MoO3辐照中提取(99m)锝的方法。本文报告了我们生产(99)钼方法的最佳条件。我们通过首次生产和分离出可用量的(99m)锝展示了该方法的成功。

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