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早期移除动脉夹的手辅助部分肾切除术:学习曲线的影响

Hand-assisted partial nephrectomy with early arterial clamp removal: Impact of the learning curve.

作者信息

Azawi Nessn H, Norus Thomas P, Wittendorff Hans-Erik, Dahl Claus

机构信息

Department of Urology, Roskilde Hospital , Roskilde , Denmark.

出版信息

Scand J Urol. 2014 Dec;48(6):538-43. doi: 10.3109/21681805.2014.925499. Epub 2014 Jun 16.

Abstract

OBJECTIVE

The aims of this study were to present the results of hand-assisted laparoscopic partial nephrectomy according to the margin, ischaemia and complications system; to assess the role of the learning curve; and to compare this approach with other approaches.

MATERIAL AND METHODS

Data from 60 consecutive patients were obtained from a prospectively maintained database. The patients were divided into three cohorts (1, 2 and 3), with 20 patients each, according to their surgery dates.

RESULTS

The overall margin, ischaemia and complications rate was 90%. The warm ischaemia time was 9.5 min in cohort 1, decreasing to 5 min in cohort 3 (p < 0.0001). The Padua score (p = 0.0287) and tumour size (p = 0.0003) were significantly increased in cohort 3, but loss of kidney function decreased significantly to 3.5% in this cohort. Loss of kidney function of less than 5% was reported for eight (40%), nine (45%) and 14 (70%) patients in cohorts 1, 2 and 3, respectively (p = 0.0185).

CONCLUSIONS

Hand-assisted laparoscopic partial nephrectomy with early removal of arterial clamps is safe and easy to learn. An expert laparoscopic surgeon can perform hand-assisted laparoscopic partial nephrectomy for complex tumours with a relatively high success rate according to the margin, ischaemia and complications system. Warm ischaemia time could be obtained within 5 min after 40 procedures.

摘要

目的

本研究旨在根据切缘、缺血及并发症系统呈现手辅助腹腔镜下部分肾切除术的结果;评估学习曲线的作用;并将该方法与其他方法进行比较。

材料与方法

从一个前瞻性维护的数据库中获取了60例连续患者的数据。根据手术日期,将患者分为三个队列(队列1、队列2和队列3),每个队列20例患者。

结果

总体切缘、缺血及并发症发生率为90%。队列1的热缺血时间为9.5分钟,队列3降至5分钟(p<0.0001)。队列3的帕多瓦评分(p=0.0287)和肿瘤大小(p=0.0003)显著增加,但该队列的肾功能丧失显著降至3.5%。队列1、队列2和队列3分别有8例(40%)、9例(45%)和14例(70%)患者报告肾功能丧失小于5%(p=0.0185)。

结论

早期移除动脉夹的手辅助腹腔镜下部分肾切除术安全且易于学习。根据切缘、缺血及并发症系统,经验丰富的腹腔镜外科医生可以为复杂肿瘤进行手辅助腹腔镜下部分肾切除术,成功率相对较高。经过40例手术后,热缺血时间可在5分钟内达到。

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