Royal Hospital, P.O. Box 2657, CPO 111 Muscat, Oman.
Department of Medicine, Royal Hospital, Muscat, Oman.
J Infect Public Health. 2014 Sep-Oct;7(5):400-6. doi: 10.1016/j.jiph.2014.04.004. Epub 2014 Jun 2.
We undertook this study to describe the epidemiological and clinical features of infective endocarditis (IE) and to study the complications and management of IE in a tertiary care hospital in Oman.
This is a retrospective study of 58 adult patients (>13 years of age) admitted to the Royal Hospital with IE from June 2006 to June 2011.
Of the 58 patients, 40 (69%) were males, and 18 (31%) were females (ratio 2.2). The median age was 43.6 years (range: 14-85). Forty-eight cases (82.7%) had native valves, nine patients (15.6%) had prosthetic valves, and one case (1.7%) had a pacemaker. The most commonly involved valves were mitral (33, 56.9%) and aortic (23, 39.7%). The blood cultures were positive in 47 (81%) patients, and the most commonly isolated organisms were Streptococci spp., which were found in 20 (34.5%) patients, and Staphylococci spp., which were found in 19 (32.8%) patients. The complication rate was 21%. A total of 15 (25.9%) patients underwent surgical intervention, and the in-hospital mortality rate was 27.6%.
Native-valve IE is the predominant type of endocarditis and is more of an acute disease. The prevalence of Staphylococci spp. IE is similar to that of Streptococci spp. IE, and its associated mortality remains high.
本研究旨在描述感染性心内膜炎（IE）的流行病学和临床特征，并研究阿曼一家三级保健医院中 IE 的并发症和处理方法。
这是一项回顾性研究，纳入了 2006 年 6 月至 2011 年 6 月期间因 IE 入住皇家医院的 58 例成年患者（>13 岁）。
58 例患者中，男性 40 例（69%），女性 18 例（31%）（比例为 2.2）。中位年龄为 43.6 岁（范围：14-85）。48 例（82.7%）为原发性心脏瓣膜疾病，9 例（15.6%）为人工心脏瓣膜疾病，1 例（1.7%）为心脏起搏器。最常受累的瓣膜是二尖瓣（33 例，56.9%）和主动脉瓣（23 例，39.7%）。血培养阳性 47 例（81%），最常分离到的病原体为链球菌属，共 20 例（34.5%），葡萄球菌属，共 19 例（32.8%）。并发症发生率为 21%。共有 15 例（25.9%）患者接受了手术干预，院内死亡率为 27.6%。
原发性心脏瓣膜 IE 是主要的 IE 类型，且更倾向于急性疾病。葡萄球菌属 IE 的患病率与链球菌属 IE 相似，但其相关死亡率仍然较高。
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