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获得性声门下狭窄:病因学特征及治疗结果

Acquired subglottic stenosis: aetiological profile and treatment results.

作者信息

Pookamala S, Thakar A, Puri K, Singh P, Kumar R, Sharma S C

机构信息

Department of Otorhinolaryngology and Head-Neck Surgery,All India Institute of Medical Sciences,New Delhi,India.

出版信息

J Laryngol Otol. 2014 Jul;128(7):641-8. doi: 10.1017/S0022215114000966. Epub 2014 Jun 16.

DOI:10.1017/S0022215114000966
PMID:24933615
Abstract

OBJECTIVES

To analyse the aetiological profile and surgical results of patients with acquired chronic subglottic stenosis, and formulate a surgical scheme based on an audit of various surgical procedures.

METHODS

Thirty patients were treated by 65 procedures (31 endoscopic and 34 external) between 2004 and 2009.

RESULTS

Isolated subglottic stenosis was noted as unusual in the majority (27 cases), demonstrating contiguous tracheal or glottic involvement. The major aetiologies were intubation injury (n = 8) and external injury (n = 21) (i.e. blunt trauma, strangulation or penetrating injury). Vocal fold immobility and cartilage framework involvement were frequent with external injury and infrequent with intubation injury. Luminal restoration was achieved by endoscopic procedures in 2 cases, external procedures in 19 cases, and external plus adjuvant endoscopic procedures in 8 cases. The preferred surgical options were: endoscopic procedures, restricted to short, recent, grade I or II mucosal stenosis cases; and external procedures for all other stenosis situations, including isolated subglottic (anterior cricoid split plus cartilage graft), subglottic and glottic or high subglottic (anterior plus posterior cricoid split with cartilage graft), and subglottic and tracheal (cricotracheal resection with anastomosis).

CONCLUSIONS

External injury stenosis has a worse profile than intubation injury stenosis. Anatomical categorisation of subglottic stenosis guides surgical procedure selection. Endoscopic procedures have limited indications as primary procedures but are useful adjunctive procedures.

摘要

目的

分析获得性慢性声门下狭窄患者的病因学特征及手术结果,并基于对各种手术方法的审核制定手术方案。

方法

2004年至2009年间,30例患者接受了65次手术(31次内镜手术和34次开放性手术)。

结果

大多数患者(27例)存在孤立性声门下狭窄,伴有连续性气管或声门受累。主要病因是插管损伤(n = 8)和外部损伤(n = 21)(即钝性创伤、勒颈或穿透伤)。声带活动障碍和软骨支架受累在外部损伤中较为常见,而在插管损伤中较少见。2例患者通过内镜手术实现管腔修复,19例通过开放性手术,8例通过开放性手术联合辅助内镜手术。首选的手术方式为:内镜手术,限于短时间内发生的I或II级黏膜狭窄病例;其他所有狭窄情况均采用开放性手术,包括孤立性声门下狭窄(环状软骨前部劈开加软骨移植)、声门下和声门或高位声门下狭窄(环状软骨前后部劈开加软骨移植)以及声门下和气管狭窄(环状气管切除并吻合)。

结论

外部损伤性狭窄比插管损伤性狭窄情况更差。声门下狭窄的解剖学分类有助于指导手术方式的选择。内镜手术作为主要手术的适应证有限,但作为辅助手术很有用。

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