Shenoy Santosh
Skinmed. 2014 Mar-Apr;12(2):114-5.
A 50-year-old heterosexual, HIV-negative man presented with a giant anal condyloma (Figure). He had iron deficiency anemia, a slow-growing anal wart for many years, and intermittent bleeding and pruritus. Esophagogastroduodenoscopy and colonoscopy findings were normal. Endoscopic ultrasound of the anorectum showed no anal sphincter involvement, and computed tomography did not reveal any pelvic inguinal lymph nodes. Wide-staged excision was performed and the patient recovered well with resolution of symptoms and no local recurrence at 1-year follow-up. Final pathology confirmed human papillomavirus (HPV) 6 strain and a giant condyloma acuminatum with mild atypia and no malignancy. Further examination of his oropharynx showed additional small HPV lesions, which were removed locally.
一名50岁的异性恋、HIV阴性男性出现巨大肛门尖锐湿疣（见图）。他患有缺铁性贫血，多年来肛门疣生长缓慢，伴有间歇性出血和瘙痒。食管胃十二指肠镜检查和结肠镜检查结果均正常。直肠肛管内镜超声显示肛门括约肌未受累，计算机断层扫描未发现盆腔腹股沟淋巴结。进行了广泛分期切除，患者恢复良好，症状缓解，1年随访时无局部复发。最终病理证实为人乳头瘤病毒（HPV）6型毒株，以及巨大尖锐湿疣伴轻度异型性且无恶性病变。对其口咽部的进一步检查发现了其他小的HPV病变，已在局部切除。
