[The changes in serum concentrations of interleukin-17 in diseases gastroduodenal zone].

THE PURPOSE OF THE STUDY

Identify on patients with chronic gastritis, peptic ulcer disease, gastric cancer, serum concentrations of interleukin-17 and its relationship to clinical and morphological and serological characteristics.

MATERIAL AND METHODS

A comprehensive survey of 156 patients with diseases gastroduodenal zone. Diagnostic emphasis was placed on ELISA method as defined in the serum of IL-17, pepsinogen-I, - II, total antibodies to CagA Helicobacter pylori.

RESULTS

In studied patients revealed changes in the concentration of interleukin-17 correlate with the stage of atrophy of the gastric mucosa, tumor, level of pepsinogen, antibodies to the Helicobacter pylori.

CONCLUSION

The data obtained allow to recommend the use of interleukin-17 in serological differential diagnosis of diseases gastroduodenal zone.