Department of Cardiothoracic Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Division of Thoracic and Cardiovascular Surgery, University of Louisville, Louisville, Ky.
J Thorac Cardiovasc Surg. 2015 Jan;149(1):116-22.e4. doi: 10.1016/j.jtcvs.2014.05.042. Epub 2014 May 21.
The purpose of the present study was to evaluate the early clinical outcomes of aortic root surgery in the United States.
The Society of Thoracic Surgeons database was queried to identify all patients who had undergone aortic root replacement from 2004 to early 2010 (n = 13,743). The median age was 58 years (range, 18-96); 3961 were women (29%) and 12,059 were white (88%). The different procedures included placement of a mechanical valve conduit (n = 4718, 34%), stented pericardial (n = 879, 6.4%) or porcine (n = 478, 3.5%) bioprosthesis, stentless root (n = 4309, 31%), homograft (n = 498, 3.6%), and valve sparing root replacement (n = 1918, 14%).
The median number of aortic root surgeries per site was 2, and only 5% of sites performed >16 aortic root surgeries annually. An increased trend to use biostented (porcine or pericardial) valves during the study period (7% in 2004 vs 14% in 2009). The operative (raw) mortality was greater among the patients with aortic stenosis (6.2%) who had undergone aortic root replacement, independent of age. Mortality was greater in patients who had undergone concomitant valve or coronary artery bypass grafting or valve surgery (21%). The lowest operative mortality was observed in patients who had undergone aortic valve sparing procedures (1.9%).
Most cardiac centers performed aortic root surgery in small volumes. The unadjusted operative mortality was greater for patients >80 years old and those with aortic stenosis, regardless of age. Valve sparing root surgery was associated with the lowest mortality. A trend was seen toward an increased use of stented tissue valves from 2004 to 2009.
本研究旨在评估美国主动脉根部手术的早期临床结果。
检索胸外科医师学会数据库,以确定 2004 年初至 2010 年初期间接受主动脉根部置换术的所有患者(n=13743)。中位年龄为 58 岁(范围,18-96 岁);3961 例为女性(29%),12059 例为白人(88%)。不同的手术方法包括机械瓣环置换(n=4718,34%)、带支架心包(n=879,6.4%)或猪(n=478,3.5%)生物瓣、无支架根部(n=4309,31%)、同种异体移植物(n=498,3.6%)和保留瓣膜的根部置换术(n=1918,14%)。
每个中心的主动脉根部手术中位数为 2 例,只有 5%的中心每年进行>16 例主动脉根部手术。在研究期间,生物瓣(猪或心包)的使用呈增加趋势(2004 年为 7%,2009 年为 14%)。主动脉根部置换术患者中,无论年龄大小,主动脉瓣狭窄患者的手术(原始)死亡率均较高(6.2%)。同时进行瓣膜或冠状动脉旁路移植术或瓣膜手术的患者死亡率较高(21%)。接受保留主动脉瓣手术的患者的手术死亡率最低(1.9%)。
大多数心脏中心进行主动脉根部手术的数量较少。无论年龄大小,80 岁以上和主动脉瓣狭窄患者的未调整手术死亡率均较高。保留瓣膜的根部手术与最低的死亡率相关。从 2004 年到 2009 年,使用带支架组织瓣的趋势呈上升趋势。