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1
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2
Bicuspid aortic valve disease and ascending aortic aneurysm: should an aortic root replacement be mandatory?†.二叶式主动脉瓣疾病与升主动脉瘤:主动脉根部置换是否应成为必要治疗手段?†
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Rev Bras Cir Cardiovasc. 2013 Oct-Dec;28(4):435-41. doi: 10.5935/1678-9741.20130072.
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本文引用的文献

1
2021 ESC/EACTS Guidelines for the management of valvular heart disease.2021年欧洲心脏病学会/欧洲心胸外科学会瓣膜性心脏病管理指南。
Eur Heart J. 2022 Feb 12;43(7):561-632. doi: 10.1093/eurheartj/ehab395.
2
The Need for the STS Score Risk Stratification System for Aortic Root Aneurysms Surgery.主动脉根部动脉瘤手术的STS评分风险分层系统的必要性。
Ann Thorac Surg. 2020 Nov;110(5):1780. doi: 10.1016/j.athoracsur.2020.03.083. Epub 2020 May 4.
3
Elective Aortic Root Replacement in North America: Analysis of STS Adult Cardiac Surgery Database.北美主动脉根部择期置换:STS 成人心脏外科学数据库分析。
Ann Thorac Surg. 2019 May;107(5):1307-1312. doi: 10.1016/j.athoracsur.2018.12.039. Epub 2019 Jan 24.
4
Association of Mortality and Acute Aortic Events With Ascending Aortic Aneurysm: A Systematic Review and Meta-analysis.升主动脉瘤与死亡率和急性主动脉事件的相关性:系统评价和荟萃分析。
JAMA Netw Open. 2018 Aug 3;1(4):e181281. doi: 10.1001/jamanetworkopen.2018.1281.
5
Aortic root surgery in the United States: a report from the Society of Thoracic Surgeons database.美国主动脉根部手术:胸外科医生协会数据库的报告。
J Thorac Cardiovasc Surg. 2015 Jan;149(1):116-22.e4. doi: 10.1016/j.jtcvs.2014.05.042. Epub 2014 May 21.
6
The Bentall procedure: is it the gold standard? A series of 597 consecutive cases.贝顿手术:它是金标准吗?一组连续 597 例病例。
J Thorac Cardiovasc Surg. 2010 Dec;140(6 Suppl):S64-70; discussion S86-91. doi: 10.1016/j.jtcvs.2010.07.033.
7
Long-term survival after the Bentall procedure in 206 patients with bicuspid aortic valve.206例二叶式主动脉瓣患者行Bentall手术后的长期生存情况。
Ann Thorac Surg. 2007 Oct;84(4):1186-93; discussion 1193-4. doi: 10.1016/j.athoracsur.2007.03.057.
8
Thoracic aortic aneurysm and dissection: increasing prevalence and improved outcomes reported in a nationwide population-based study of more than 14,000 cases from 1987 to 2002.胸主动脉瘤和夹层:在一项基于全国人口的研究中报告显示,1987年至2002年期间超过14000例病例的患病率增加且预后改善。
Circulation. 2006 Dec 12;114(24):2611-8. doi: 10.1161/CIRCULATIONAHA.106.630400. Epub 2006 Dec 4.
9
Marfan's syndrome.马方综合征
Lancet. 2005 Dec 3;366(9501):1965-76. doi: 10.1016/S0140-6736(05)67789-6.
10
Composite aortic root replacement in acute type A dissection: time to rethink the indications?急性A型主动脉夹层的复合主动脉根部置换术:是时候重新审视手术指征了吗?
Eur J Cardiothorac Surg. 2005 Apr;27(4):626-32; discussion 632-3. doi: 10.1016/j.ejcts.2004.12.059.

主动脉根部病变与外科治疗:来自一位外科医生经验的见解

Aortic Root Pathologies and Surgical Management: Insights From a Single Surgeon's Experience.

作者信息

Aasim Muhammad, Aziz Raheela, Mohsin Atta Ul, Khan Raheel, Aziz Gulshad, Zahid Ayesha, Srinivasan Aariya, Ikram Jibran

机构信息

Cardiac Surgery, Hayatabad Medical Complex, Peshawar, PAK.

Cardiac Surgery, Khyber Girls Medical College (KGMC), Peshawar, PAK.

出版信息

Cureus. 2024 Nov 20;16(11):e74096. doi: 10.7759/cureus.74096. eCollection 2024 Nov.

DOI:10.7759/cureus.74096
PMID:39712720
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11661876/
Abstract

Introduction and objectives The Bentall procedure is a surgical technique designed to address aortic root abnormalities, including issues with the aortic valve, aortic root, and ascending aortic disease. This study aimed to assess the short-term outcomes of 39 patients who underwent the Bentall and concomitant procedures: aortic root enlargement, personalized external aortic root support (PEARS), and Mini-Bentall procedures at a single center. Methodology We conducted a retrospective study involving 39 patients who underwent surgery for aortic root pathologies such as dissection, Marfan syndrome (MFS), bicuspid aortic valve, degenerative disease, and atherosclerosis at our hospital between January 2019 and September 2024. Data were collected from clinical records and were utilized for statistical analysis. Results In this study of 39 patients (average age 43.97 ± 17.45 years; 71.8% male), hypertension was the most common risk factor (46.2%). The early mortality rate was 2.6%, with one death from bleeding. Dissection and MFS were the leading causes of aortic root pathologies (35.9% each). Coexisting heart diseases were found in 20.5% of patients. Emergency and urgent surgeries accounted for 38.5% and 53.8%, respectively. Bentall surgery was performed in 64.4% of cases, with average cardiopulmonary bypass (CPB) and cross-clamp times of 196.10 ± 25.23 and 169.05 ± 23.9 minutes, respectively. Conclusion Overall, the hospital mortality rate for the Bentall procedure at our institution was 2.6%, consistent with the reported literature. Our results show that, although complex, the classic Bentall technique can be performed safely with acceptable short-term morbidity and mortality. Addressing complications like hospital mortality and postoperative bleeding is crucial, as these issues may be preventable.

摘要

引言与目的

Bentall手术是一种旨在解决主动脉根部异常的外科技术,包括主动脉瓣、主动脉根部及升主动脉疾病相关问题。本研究旨在评估在单一中心接受Bentall及相关手术(主动脉根部扩大术、个性化体外主动脉根部支撑术(PEARS)和Mini - Bentall手术)的39例患者的短期预后。

方法

我们进行了一项回顾性研究,纳入了2019年1月至2024年9月期间在我院因主动脉根部病变(如夹层、马凡综合征(MFS)、二叶式主动脉瓣、退行性疾病和动脉粥样硬化)接受手术的39例患者。数据从临床记录中收集并用于统计分析。

结果

在这项对39例患者(平均年龄43.97±17.45岁;71.8%为男性)的研究中,高血压是最常见的危险因素(46.2%)。早期死亡率为2.6%,1例死于出血。夹层和MFS是主动脉根部病变的主要原因(各占35.9%)。20.5%的患者存在合并心脏病。急诊和限期手术分别占38.5%和53.8%。64.4%的病例进行了Bentall手术,平均体外循环(CPB)时间和主动脉阻断时间分别为196.10±25.23分钟和169.05±23.9分钟。

结论

总体而言,我院Bentall手术的院内死亡率为2.6%,与报道的文献一致。我们的结果表明,尽管该技术复杂,但经典的Bentall技术可以安全实施,短期发病率和死亡率可接受。处理如院内死亡和术后出血等并发症至关重要,因为这些问题可能是可预防的。