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减重手术后的医院获得性疾病:我们能够预测,但能够预防吗?

Hospital-acquired conditions after bariatric surgery: we can predict, but can we prevent?

作者信息

Lidor Anne O, Moran-Atkin Erin, Stem Miloslawa, Magnuson Thomas H, Steele Kimberley E, Feinberg Richard, Schweitzer Michael A

机构信息

Department of Surgery, Johns Hopkins University School of Medicine, Johns Hopkins Hospital, 600 N. Wolfe Street, Blalock 618, Baltimore, MD, 21287, USA,

出版信息

Surg Endosc. 2014 Dec;28(12):3285-92. doi: 10.1007/s00464-014-3602-y. Epub 2014 Jun 17.

Abstract

BACKGROUND

Centers for Medicare and Medicaid Services initiated a non-payment policy for certain hospital-acquired conditions (HACs) in 2008. This study aimed to determine the rate of the three most common HACs (surgical site infection (SSI), urinary tract infection (UTI), and venous thromboembolism (VTE)) among bariatric surgery patients. Additionally, the association of HACs with patient factors and the effect of HACs on post-operative outcomes were investigated.

METHODS

Patients over 18 years with a body mass index (BMI) ≥ 35 who underwent bariatric surgery were identified using the American College of Surgeons' National Surgical Quality Improvement Program (ACS-NSQIP) database (2005-2012). Patients were grouped into two categories: HAC versus no HAC patients and baseline characteristics and outcomes, including 30-day mortality, reoperation, and mean length of stay (LOS) were compared. Multivariable logistic regression analysis was performed to identify the risk factors for developing a HAC.

RESULTS

98,553 patients were identified, 2,809 (2.9%) developed at least one HACs. SSI was the most common HAC (1.8%), followed by UTI (0.7%) and VTE (0.4%). The rate of these HACs significantly decreased from 4.6% in 2005-2006 to 2.5% in 2012 (p < 0.001). Laparoscopic gastric banding was associated with the lowest rates of HAC (1.3%) and open gastric bypass with the highest (8.0%). HAC patients had significantly higher rates of in-hospital mortality (0.8 vs. 0.1%, p < 0.001) and LOS (3.9 vs. 2.1 days, p < 0.001). On adjusted analysis, open GBP patients had 5.36-fold higher odds of developing a HAC. Interestingly, the presence of a resident surgeon 7-11 years post graduation was associated with significantly increased odds of HACs (1.86, 1.50-2.31, p < 0.001).

CONCLUSION

Our data demonstrate a strong correlation between these three HACs following bariatric surgery and factors intrinsic to the bariatric patient population. This calls into question the non-payment policy for inherent patient factors on which they cannot have impact. These findings are important to help inform health care policy decisions regarding access to care for bariatric surgery patients.

摘要

背景

医疗保险和医疗补助服务中心于2008年针对某些医院获得性疾病(HACs)启动了一项不予支付政策。本研究旨在确定肥胖症手术患者中三种最常见的医院获得性疾病(手术部位感染(SSI)、尿路感染(UTI)和静脉血栓栓塞症(VTE))的发生率。此外,还研究了医院获得性疾病与患者因素之间的关联以及医院获得性疾病对术后结局的影响。

方法

使用美国外科医师学会的国家外科质量改进计划(ACS-NSQIP)数据库(2005 - 2012年)确定年龄在18岁以上、体重指数(BMI)≥35且接受过肥胖症手术的患者。将患者分为两类:发生医院获得性疾病的患者与未发生医院获得性疾病的患者,并比较其基线特征和结局,包括30天死亡率、再次手术率和平均住院时间(LOS)。进行多变量逻辑回归分析以确定发生医院获得性疾病的危险因素。

结果

共识别出98,553例患者,其中2,809例(2.9%)发生了至少一种医院获得性疾病。手术部位感染是最常见的医院获得性疾病(1.8%),其次是尿路感染(0.7%)和静脉血栓栓塞症(0.4%)。这些医院获得性疾病的发生率从2005 - 2006年的4.6%显著下降至2012年的2.5%(p < 0.001)。腹腔镜胃束带术的医院获得性疾病发生率最低(1.3%),而开放式胃旁路手术的发生率最高(8.0%)。发生医院获得性疾病的患者院内死亡率(0.8%对0.1%,p < 0.001)和住院时间(3.9天对2.1天,p < 0.001)显著更高。经调整分析,开放式胃旁路手术患者发生医院获得性疾病的几率高5.36倍。有趣的是,毕业后7 - 11年的住院医师参与手术与医院获得性疾病的几率显著增加相关(1.86,1.50 - 2.31,p < 0.001)。

结论

我们的数据表明,肥胖症手术后这三种医院获得性疾病与肥胖症患者群体的内在因素之间存在密切关联。这使得针对患者无法影响的固有因素的不予支付政策受到质疑。这些发现对于为肥胖症手术患者的医疗保健政策决策提供参考具有重要意义。

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