Armenta Sergio, Garrigues Salvador, de la Guardia Miguel, Brassier Judit, Alcalà Manel, Blanco Marcelo, Perez-Alfonso Clara, Galipienso Nieves
Department of Analytical Chemistry, Research Building, University of Valencia, 50 Dr. Moliner St, E-46100, Burjassot, Valencia, Spain.
Drug Test Anal. 2015 Apr;7(4):280-9. doi: 10.1002/dta.1678. Epub 2014 Jun 16.
Rapid detection and identification of novel psychoactive substances (NPS) continues to present significant analytical challenges to forensic and analytical chemists. Ion mobility spectrometry (IMS) has been traditionally considered as the analytical technique of choice to detect illicit drugs in security points in airports, borderlines and customs. Databases of the reduced mobility (K0 ) values of illicit drugs are available in the scientific literature and they should be completed with data of emerging designer drugs. In this paper, we have evaluated the effect of different measurement conditions and determined the K0 values of an important number of NPS including different families; such as phenethylamines, cathinones, synthetic cannabinoids and tryptamines among others to be incorporated to the existing data to provide a rapid detection and identification of this emerging threat.
新型精神活性物质（NPS）的快速检测和鉴定仍然给法医和分析化学家带来重大的分析挑战。传统上，离子迁移谱（IMS）被视为在机场、边境和海关等安检点检测非法药物的首选分析技术。科学文献中已有非法药物的折合迁移率（K0）值数据库，这些数据库应补充新型设计药物的数据。在本文中，我们评估了不同测量条件的影响，并确定了大量NPS（包括不同类别，如苯乙胺类、卡西酮类、合成大麻素类和色胺类等）的K0值，以便将这些数据纳入现有数据，从而实现对这一新兴威胁的快速检测和鉴定。
