检测非洲体虱和头虱中的五日热巴通体。
Detection of Bartonella quintana in African body and head lice.
机构信息
Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Unité Mixte de Recherche (UMR)63, 7278 Centre National de la Recherche Scientifique (CNRS), Institut de Recherche pour le Développement (IRD) 198, Institut National de la Santé et de la Recherche Médicale (INSERM) 1095, University of Aix, Marseille, France; IRD, Campus Commun Université Cheikh Anta Diop (UCAD)-IRD of Hann, Dakar, Senegal; Parasitology Section, School of Chemistry and Molecular Biosciences (SCMB), University of Queensland, Brisbane, Queensland, Australia; Pasteur Institute of Madagascar, Ambohitrakely, Madagascar; University of Bamako, Malaria Research and Training Center (MRTC)/Département d'Epidemiologie des Affections Parasitaires (DEAP)/Faculté de Médecine de Pharmacie et d'Odontostomatologie (FMPOS)-Unité Mixte Internationale (UMI)3189, Bamako, Mali.
Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Unité Mixte de Recherche (UMR)63, 7278 Centre National de la Recherche Scientifique (CNRS), Institut de Recherche pour le Développement (IRD) 198, Institut National de la Santé et de la Recherche Médicale (INSERM) 1095, University of Aix, Marseille, France; IRD, Campus Commun Université Cheikh Anta Diop (UCAD)-IRD of Hann, Dakar, Senegal; Parasitology Section, School of Chemistry and Molecular Biosciences (SCMB), University of Queensland, Brisbane, Queensland, Australia; Pasteur Institute of Madagascar, Ambohitrakely, Madagascar; University of Bamako, Malaria Research and Training Center (MRTC)/Département d'Epidemiologie des Affections Parasitaires (DEAP)/Faculté de Médecine de Pharmacie et d'Odontostomatologie (FMPOS)-Unité Mixte Internationale (UMI)3189, Bamako, Mali
出版信息
Am J Trop Med Hyg. 2014 Aug;91(2):294-301. doi: 10.4269/ajtmh.13-0707. Epub 2014 Jun 16.
Currently, the body louse is the only recognized vector of Bartonella quintana, an organism that causes trench fever. In this work, we investigated the prevalence of this bacterium in human lice in different African countries. We tested 616 head lice and 424 body lice from nine African countries using real-time polymerase chain reaction targeting intergenic spacer region 2 and specific B. quintana genes. Overall, B. quintana DNA was found in 54% and 2% of body and head lice, respectively. Our results also show that there are more body lice positive for B. quintana in poor countries, which was determined by the gross domestic product, than in wealthy areas (228/403 versus 0/21, P < 0.001). A similar finding was obtained for head lice (8/226 versus 2/390, P = 0.007). Our findings suggest that head lice in Africa may be infected by B. quintana when patients live in poor economic conditions and are also exposed to body lice.
目前，体虱是唯一被确认可传播引起战壕热的巴尔通体（Bartonella quintana）的媒介。在这项工作中，我们调查了不同非洲国家人体虱中这种细菌的流行情况。我们使用针对种间 spacer 区域 2 和特定 B. quintana 基因的实时聚合酶链反应，对来自九个非洲国家的 616 个头虱和 424 个体虱进行了检测。总体而言，分别有 54%和 2%的体虱和头虱携带 B. quintana DNA。我们的结果还表明，在国内生产总值较低的贫穷国家，感染 B. quintana 的体虱比富裕地区更多（228/403 与 0/21，P<0.001）。对头虱也有类似的发现（8/226 与 2/390，P=0.007）。我们的研究结果表明，当患者生活在经济条件较差且同时接触体虱的情况下，非洲的头虱可能会感染 B. quintana。
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