Jones R, Silverstein H, Smouha E
Ear Research Foundation, Sarasota, FL 34239.
Otolaryngol Head Neck Surg. 1989 Jan;100(1):22-9. doi: 10.1177/019459988910000104.
One hundred patients have been treated over a 13-year period with a transmeatal approach to the internal auditory canal for cochleovestibular neurectomy. Ninety-one of these patients have followup of more than 3 months (average, 4.67 years). The most common indication for the procedure was Meniere's disease (71%). Chronic labyrinthitis, usually following stapes, middle ear, or mastoid surgery, was the next most common indication. Patients with the preoperative diagnosis of Meniere's disease had better results in the curing of vertigo (89%) than those having chronic labyrinthitis (68%). Overall, vertigo was cured in 84% of patients and markedly improved in another 15.1%. Tinnitus was relieved or improved in 65% of all patients and in 67% of patients with Meniere's disease. Mild unsteadiness was commonly noticed postoperatively, but only 11% described this as severe. Eighty percent of these latter patients reported unsteadiness preoperatively. Complications were uncommon and temporary: one case of delayed facial paresis that recovered completely, one CSF leak, and one wound infection. There were no cases of permanent facial paralysis or meningitis. The advantages of the transmeatal approach to the IAC for CVN over labyrinthectomy without CVN are assurance of complete labyrinthine denervation, increased likelihood of improved tinnitus, practice at sectioning the posterior ampullary nerve (PAN), and the ability to inspect the internal auditory canal for a small tumor or other pathology. We recommend this procedure for treatment of unilateral vestibular dysfunction in patients with no serviceable hearing.
在13年期间,采用经耳道入路至内耳道进行耳蜗前庭神经切除术治疗了100例患者。其中91例患者随访时间超过3个月(平均4.67年)。该手术最常见的适应证是梅尼埃病(71%)。慢性迷路炎,通常继发于镫骨手术、中耳手术或乳突手术后,是第二常见的适应证。术前诊断为梅尼埃病的患者在眩晕治愈方面(89%)比患有慢性迷路炎的患者(68%)效果更好。总体而言,84%的患者眩晕得到治愈,另有15.1%的患者明显改善。65%的所有患者耳鸣得到缓解或改善,梅尼埃病患者中这一比例为67%。术后常出现轻度不稳感,但只有11%的患者称其严重。后一组患者中有80%术前就有不稳感。并发症不常见且为暂时性:1例迟发性面神经麻痹完全恢复,1例脑脊液漏,1例伤口感染。无永久性面瘫或脑膜炎病例。与不进行耳蜗前庭神经切除术的迷路切除术相比,经耳道入路至内耳道进行耳蜗前庭神经切除术的优点包括确保完全迷路去神经支配、耳鸣改善可能性增加、可练习切断后半规管壶腹神经(PAN)以及能够检查内耳道有无小肿瘤或其他病变。对于无有用听力的单侧前庭功能障碍患者,我们推荐该手术。