Cameron J S
Renal Unit, United Medical and Dental Schools, London, England.
Adv Nephrol Necker Hosp. 1989;18:207-48.
Tubulointerstitial disease has been reviewed twice in the past five years at the Necker Seminars in Nephrology; why is it necessary to return once again to this topic? Although the importance of the tubulointerstitial component of the kidney is self-evident, the literature on glomerular disease remains vastly greater than that on the tubules and interstitium. In this brief review I wish first to discuss the tubulointerstitial component of what are usually considered glomerular diseases--the glomerulonephritides and lupus, and then to discuss what appear to be primary tubulointerstitial nephritides (TIN), in which the glomeruli are usually spared and the primary attack appears to be on the tubules and interstitium.
在过去五年里，关于肾小管间质疾病的内容已在奈克肾脏学研讨会上被两次回顾；为何有必要再次回到这个话题呢？尽管肾脏的肾小管间质部分的重要性不言而喻，但关于肾小球疾病的文献仍远多于关于肾小管和间质的文献。在这篇简短的综述中，我首先想讨论通常被认为是肾小球疾病（肾小球肾炎和狼疮）中的肾小管间质部分，然后再讨论似乎是原发性肾小管间质性肾炎（TIN）的疾病，在这些疾病中，肾小球通常未受影响，主要病变似乎发生在肾小管和间质。
