Bamaiyi A J, Adelaiye A B, Igbokwe V U
Department of Physiology, College of Health Sciences, Usmanu Danfodiyo University, Sokoto.
Niger J Physiol Sci. 2013 Dec 20;28(2):211-9.
The pregnancy state in a woman's life is a unique state in terms of the desirable physiological changes and the exciting reversal of the changes soon after the termination of the pregnancy. It is considered essential that to guarantee a good feto-maternal outcome the attainment of optimum anthropometric and haematological parameters are key. Our study assessed the anthropometric and haematological changes and also looked at the relationship that exists between these parameters among pregnant women.We carried out a cross-sectional descriptive study which considered 160 apparently healthy, singleton, third trimester pregnant women attending ANC at the State Specialist Hospital and 58 apparently healthy non-pregnant controls sourced from the Sokoto metropolis population. Each subject or control enrolled was contacted 3 times at 2 weekly intervals. And at each occasion they are assessed for changes in the anthropometric and haematological parameters. The response rate was 93.6% (3 pregnants and 11 controls were loss to follow up). The pregnant and control subgroups mean ages were 28.02 ± 6.81 years and 26.89 ± 5.84 years respectively (p = 0.265). Weekly weight gains of 0.48kg among the pregnant sub-group against 0.13kg obtained in the control group were recorded. BMI increase of about 0.19kg/m2 per week among the pregnant sub-group and only 0.05kg per week in the controls. 95% of the distribution of pregnant sub-group has haemoglobin and haematocrit of ≥8.9g/dL and ≥26% respectively. Among the pregnant sub-group, mean weekly haemoglobin and haematocrit drop of 0.24g/dL and 0.74% were respectively recorded. A steady rise in WBC was recorded but platelets counts dropped at an average of 5.04 x 103 /μL per week. A positive correlation between BMI and haemoglobin levels was observed (r > 0 and p < 0.05). No particular regularity in the relationship between BMI and WBC was noticed. We conclude that there was optimum weight gain and good haematological indices for those with good BMI during the third trimester of pregnancy. There was a positive correlation between BMI and plasma haemoglobin level but WBC showed no particular relationship with the anthropometric changes. We therefore, recommend that good education to improve the socio- economic wellbeing of the girl-child be encouraged to boost self sufficiency for better weight gains and to facilitate access to good healthcare so that the ideal anthropometric and haematological parameters can be achieved during pregnancy to guarantee good feto-maternal outcome.
女性孕期在生理变化方面是一种独特的状态，且在妊娠终止后不久这些变化会令人兴奋地逆转。人们认为，确保母婴获得良好结局的关键在于达到最佳人体测量学和血液学参数。我们的研究评估了人体测量学和血液学变化，并观察了孕妇这些参数之间的关系。我们进行了一项横断面描述性研究，研究对象包括160名在州立专科医院接受产前护理的、表面健康的单胎妊娠晚期孕妇，以及58名从索科托市人口中选取的表面健康的非孕妇对照。每一位纳入的受试者或对照每隔一周被联系3次。每次都对他们的人体测量学和血液学参数变化进行评估。应答率为93.6%（3名孕妇和11名对照失访）。孕妇亚组和对照亚组的平均年龄分别为28.02±6.81岁和26.89±5.84岁（p=0.265）。记录到孕妇亚组每周体重增加0.48kg，而对照组为0.13kg。孕妇亚组BMI每周增加约0.19kg/m²，而对照组仅为每周0.05kg。孕妇亚组95%的血红蛋白和血细胞比容分布分别≥8.9g/dL和≥26%。在孕妇亚组中，记录到血红蛋白和血细胞比容每周平均下降0.24g/dL和0.74%。白细胞呈稳步上升，但血小板计数平均每周下降5.04×10³/μL。观察到BMI与血红蛋白水平呈正相关（r>0且p<0.05）。未发现BMI与白细胞之间存在特定规律。我们得出结论，在妊娠晚期，BMI良好的孕妇体重增加最佳且血液学指标良好。BMI与血浆血红蛋白水平呈正相关，但白细胞与人体测量学变化无特定关系。因此，我们建议鼓励开展良好教育以改善女童的社会经济福祉，增强自给自足能力以实现更好的体重增加，并促进获得良好的医疗保健，以便在孕期达到理想的人体测量学和血液学参数，确保母婴获得良好结局。
