Suppr超能文献

原发性脊柱感染患者的脊柱内固定术不会导致更高的复发感染率:118例病例分析。

Spinal instrumentation in patients with primary spinal infections does not lead to greater recurrent infection rates: an analysis of 118 cases.

作者信息

Bydon Mohamad, De la Garza-Ramos Rafael, Macki Mohamed, Naumann Matthew, Sciubba Daniel M, Wolinsky Jean-Paul, Bydon Ali, Gokaslan Ziya L, Witham Timothy F

机构信息

The Spinal Column Biomechanics and Surgical Outcomes Laboratory, Johns Hopkins Hospital, Baltimore, Maryland, USA; Department of Neurosurgery, Johns Hopkins Hospital, Baltimore, Maryland, USA.

The Spinal Column Biomechanics and Surgical Outcomes Laboratory, Johns Hopkins Hospital, Baltimore, Maryland, USA.

出版信息

World Neurosurg. 2014 Dec;82(6):e807-14. doi: 10.1016/j.wneu.2014.06.014. Epub 2014 Jun 14.

Abstract

OBJECTIVE

We sought to compare outcomes between patients undergoing decompression only versus decompression and instrumented fusion for primary spinal infections.

METHODS

Records of patients with a diagnosis of primary spinal infection who underwent surgical management at our institution during a 10-year period were reviewed. Patients were divided into 2 cohorts based on treatment received (decompression alone vs. decompression and instrumentation). Our primary end points were complication rates, need for reoperation, recurrent infections, and resolution of symptom(s) at last follow-up.

RESULTS

A total of 118 patients underwent surgical management for primary spinal infections. Thirty-five patients presented with a cervical spine infection, 40 with a thoracic infection, and 43 with a lumbosacral infection. The mean age at presentation was 57.1 ± 13.5 years. Thirty-six patients underwent only decompression, and 82 underwent decompression and instrumented fusion. In the decompression-only group, 8.33% of patients had continued osteomyelitis/discitis compared with 9.76% of patients in the instrumented group (P = 0.807). Importantly, the reoperation rate was also similar between the decompression-only group (19.44%) and the instrumented group (17.07%; P = 0.756). Similarly, subanalyses based on infection location revealed no significant increase in rates of recurrent infection or reoperation in patients who underwent instrumentation.

CONCLUSION

Patients who received just decompression for spinal infection had similar reoperation and continued infection rates as patients who additionally underwent instrumentation, irrespective of infection location within the spine. These findings suggest that instrumentation of the infected spine may be a safe treatment modality and should be considered when the spinal integrity is compromised.

摘要

目的

我们试图比较仅接受减压治疗与接受减压及器械融合治疗的原发性脊柱感染患者的治疗结果。

方法

回顾了我院在10年期间对诊断为原发性脊柱感染并接受手术治疗的患者的记录。根据接受的治疗(单纯减压与减压及器械固定)将患者分为两组。我们的主要终点是并发症发生率、再次手术需求、复发性感染以及末次随访时症状的缓解情况。

结果

共有118例患者接受了原发性脊柱感染的手术治疗。35例患者为颈椎感染,40例为胸椎感染,43例为腰骶部感染。就诊时的平均年龄为57.1±13.5岁。36例患者仅接受了减压治疗,82例患者接受了减压及器械融合治疗。在单纯减压组中,8.33%的患者持续存在骨髓炎/椎间盘炎,而器械固定组为9.76%(P = 0.807)。重要的是,单纯减压组(19.44%)和器械固定组(17.07%;P = 0.756)的再次手术率也相似。同样,根据感染部位进行的亚组分析显示,接受器械固定的患者复发性感染或再次手术率没有显著增加。

结论

脊柱感染仅接受减压治疗的患者与额外接受器械固定的患者相比,再次手术率和持续感染率相似,无论脊柱内的感染部位如何。这些发现表明,感染脊柱的器械固定可能是一种安全的治疗方式,当脊柱完整性受到损害时应予以考虑。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验