Sheng S-C, Lu X-M, Kang Y, Du Y-P, Wang G-X
Department of Clinical Laboratory, the Second People's Hospital of Yibin City, Sichuan, Province, China.
Department of Cardiology, the Second People's Hospital of Yibin City, Sichuan Province, China.
Genet Mol Res. 2014 May 16;13(2):3819-25. doi: 10.4238/2014.May.16.6.
High-sensitivity cardiac troponin T is a useful tool for diagnosing myocardial ischemia. However, its role in the prognosis of patients with acute myocardial infarction has not been studied. Here, the prognostic value of high-sensitivity cardiac troponin T for patients with acute myocardial infarction was investigated. The concentrations of high-sensitivity cardiac troponin T, other clinical chemistry makers, and living habits were investigated at the time of admission in patients with acute coronary syndrome, whereas the high-sensitivity cardiac troponin T concentrations at 6 h after admission and during recovery were analyzed in other patient groups. The concentration of high-sensitivity cardiac troponin T was significantly higher in patients with acute myocardial infarction than in those with other cardiac diseases and in controls (P < 0.01). Based on the standard diagnostic criterion, 134 patients were diagnosed with acute myocardial infarction. Monitoring the change in concentration of high-sensitivity cardiac troponin T in patients with acute coronary syndrome can reduce the risk of recurrence and death.
高敏心肌肌钙蛋白T是诊断心肌缺血的有用工具。然而，其在急性心肌梗死患者预后中的作用尚未得到研究。在此，研究了高敏心肌肌钙蛋白T对急性心肌梗死患者的预后价值。对急性冠状动脉综合征患者入院时高敏心肌肌钙蛋白T的浓度、其他临床化学指标和生活习惯进行了调查，而对其他患者组分析了入院后6小时及恢复期间的高敏心肌肌钙蛋白T浓度。急性心肌梗死患者的高敏心肌肌钙蛋白T浓度显著高于其他心脏病患者和对照组（P<0.01）。根据标准诊断标准，134例患者被诊断为急性心肌梗死。监测急性冠状动脉综合征患者高敏心肌肌钙蛋白T浓度的变化可降低复发和死亡风险。
