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外阴阴道萎缩继发性交困难的治疗。

Treatment of dyspareunia secondary to vulvovaginal atrophy.

作者信息

Fantasia Heidi Collins

出版信息

Nurs Womens Health. 2014 Jun-Jul;18(3):237-41. doi: 10.1111/1751-486X.12125.

DOI:10.1111/1751-486X.12125
PMID:24939201
Abstract

Declining estrogen levels associated with menopause can result in vulvovaginal atrophy and some degree of dyspareunia for more than half of all women in menopause. In 2013, the U.S. Food and Drug Administration approved ospemifene, a nonhormonal oral medication for the treatment of dyspareunia in menopause. This article will provide an overview of ospemifene and its indications, side effects and implications for nurses.

摘要

与绝经相关的雌激素水平下降会导致超过半数的绝经女性出现外阴阴道萎缩和一定程度的性交困难。2013年,美国食品药品监督管理局批准了奥培米芬,一种用于治疗绝经后性交困难的非激素类口服药物。本文将概述奥培米芬及其适应证、副作用以及对护士的意义。

相似文献

1
Treatment of dyspareunia secondary to vulvovaginal atrophy.外阴阴道萎缩继发性交困难的治疗。
Nurs Womens Health. 2014 Jun-Jul;18(3):237-41. doi: 10.1111/1751-486X.12125.
2
Ospemifene: a first-in-class, non-hormonal selective estrogen receptor modulator approved for the treatment of dyspareunia associated with vulvar and vaginal atrophy.奥培米芬:一种一流的非激素选择性雌激素受体调节剂,已获批用于治疗与外阴和阴道萎缩相关的性交困难。
Steroids. 2014 Nov;90:82-93. doi: 10.1016/j.steroids.2014.07.012. Epub 2014 Aug 1.
3
Safety and efficacy of ospemifene for the treatment of dyspareunia associated with vulvar and vaginal atrophy due to menopause.奥培米芬治疗绝经引起的外阴和阴道萎缩相关性交困难的安全性和有效性。
Clin Interv Aging. 2014 Nov 13;9:1939-50. doi: 10.2147/CIA.S73753. eCollection 2014.
4
Ospemifene for the treatment of vulvovaginal atrophy and dyspareunia in postmenopausal women.奥司米芬用于治疗绝经后女性的外阴阴道萎缩和性交困难。
Pharmacotherapy. 2014 Oct;34(10):1050-60. doi: 10.1002/phar.1465. Epub 2014 Jul 23.
5
The efficacy and safety of ospemifene in treating dyspareunia associated with postmenopausal vulvar and vaginal atrophy: a systematic review and meta-analysis.奥昔布宁治疗绝经后外阴和阴道萎缩相关性交困难的疗效和安全性:系统评价和荟萃分析。
J Sex Med. 2014 Feb;11(2):487-97. doi: 10.1111/jsm.12377. Epub 2013 Nov 20.
6
Ospemifene in the treatment of vulvovaginal atrophy.奥司米芬治疗外阴阴道萎缩
Ann Pharmacother. 2014 Jun;48(6):752-7. doi: 10.1177/1060028014526036. Epub 2014 Mar 10.
7
Ospemifene: a novel selective estrogen receptor modulator for treatment of dyspareunia.奥昔芬:一种用于治疗性交困难的新型选择性雌激素受体调节剂。
Womens Health (Lond). 2014 Sep;10(5):499-503. doi: 10.2217/whe.14.46.
8
Ospemifene, a novel selective estrogen receptor modulator for treating dyspareunia associated with postmenopausal vulvar and vaginal atrophy.奥昔布宁,一种新型选择性雌激素受体调节剂,用于治疗绝经后外阴和阴道萎缩相关的性交困难。
Menopause. 2013 Jun;20(6):623-30. doi: 10.1097/gme.0b013e318279ba64.
9
Long-term safety of ospemifene (52-week extension) in the treatment of vulvar and vaginal atrophy in hysterectomized postmenopausal women.在子宫切除术后绝经后妇女的外阴和阴道萎缩的治疗中,奥昔孕诺(52 周扩展)的长期安全性。
Maturitas. 2014 Mar;77(3):274-81. doi: 10.1016/j.maturitas.2013.12.005. Epub 2013 Dec 17.
10
Ospemifene: A Novel Oral Therapy for Vulvovaginal Atrophy of Menopause.欧斯泊芬:一种治疗绝经后女性阴道萎缩的新型口服药物。
J Obstet Gynaecol Can. 2020 Mar;42(3):301-303. doi: 10.1016/j.jogc.2019.10.039. Epub 2020 Jan 10.

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Patient-Physician Interactions Regarding Dyspareunia with Endometriosis: Online Survey Results.关于子宫内膜异位症相关性交困难的医患互动:在线调查结果。
J Pain Res. 2020 Jun 29;13:1579-1589. doi: 10.2147/JPR.S248887. eCollection 2020.