Krishnappa Lakshmana Gowda, Marie Mohammed Ali M, John James, Dabwan Khaled Homoud M, Shashidhar Pradeep Chikkabidare
King Saud University Department of Clinical Laboratory Sciences, College of Applied Medical Sciences Po Box 10219 Riyadh 11433 Saudi Arabia.
Loyola College (Autonomous) Department of Zoology and Advance Biotechnology Chennai India.
Acta Microbiol Immunol Hung. 2014 Jun;61(2):173-9. doi: 10.1556/AMicr.61.2014.2.7.
Streptococcus pneumoniae causes life threatening infections and necessitate for impediment and controlling disease; to conquer this, information is needed about serotype distribution and patterns of antibiotic resistance. The present study was to determine the serotype distribution of S. pneumoniae isolated from the entire age group individual and to correlate this distribution with susceptibility. Cases of pneumococcal infections have been reviewed for serotyping and antibiotic susceptibility. Out of 117 pneumococcal isolates 45 (39%) were penicillin-resistant, 84 (72%) were erythromycin-resistant and 100% were co-trimoxazole resistant. The most frequently isolated serotypes were 23F, 19F, 14, 6B, 5, 6A, 19A and 9V. PCV7, PCV10 and PCV13 coverage was 68%, 79%, 87%, respectively. Similarly, there was similarity in PCV7 coverage for non invasive isolates (64.5%) and invasive isolates (72.2%). The study state that common pneumococcal serotypes were present in similar ways as reported in literature. A continuous survey of pneumococcal infected population is requirement and necessity for success of vaccination.
肺炎链球菌可引发危及生命的感染，因此需要采取措施预防和控制该疾病；为实现这一目标，需要了解血清型分布及抗生素耐药模式。本研究旨在确定从各年龄段个体分离出的肺炎链球菌的血清型分布，并将这种分布与药敏性相关联。已对肺炎球菌感染病例进行血清分型和抗生素敏感性分析。在117株肺炎球菌分离株中，45株（39%）对青霉素耐药，84株（72%）对红霉素耐药，100%对复方新诺明耐药。最常分离出的血清型为23F、19F、14、6B、5、6A、19A和9V。PCV7、PCV10和PCV13的覆盖率分别为68%、79%、87%。同样，非侵袭性分离株（64.5%）和侵袭性分离株（72.2%）的PCV7覆盖率相似性。该研究表明，常见肺炎球菌血清型的存在方式与文献报道相似。持续监测肺炎球菌感染人群是疫苗接种成功的必要条件。
