Villaverde-Hueso A, Alonso V, Morales-Piga A, Hens-Pérez M, Abaitua I, Posada-de-la-Paz M
Institute of Rare Diseases Research, Instituto de Salud Carlos III. Madrid, Spain; Centre for Biomedical Network Research on Rare Diseases (CIBERER) and Spanish Rare Diseases Registries Research Network (Spain RDR).
Georgian Med News. 2014 May(230):65-72.
The aim of this study is to describe the childhood vasculitis hospital burden in Spain (1997-2011), considering type of disease, hospitalization rates and time trends. Data were obtained from the National Discharges Basic Minimum Data Set (National Patient Data Base). Inpatient events of children younger than 15 years of age were analyzed. Principal diagnosis of vasculitis were selected according Ninth Revision of the International Classification of Diseases: Takayasu arteritis, Polyarteritis nodosa, Kawasaki disease, Wegener`s granulomatosis, Churg-Strauss syndrome, and Henoch-Schönlein purpura. A total of 14518 children hospitalizations related to vasculitis were identified in Spain from 1997 to 2011. The average hospitalization rate for children was 13.33±1.71 per 100,000. Henoch-Schönlein purpura and Kawasaki disease were the most common type of vasculitis, hospitalization rates were 11.00 and 3.97 per 100,000 children, respectively. Other vasculitis hospitalizations are much rare in childhood. Average length of stay was 6.04 days and estimated cost per inpatient hospital care was 2,847€. Hospital case fatality rate was 0.05% for overall vasculitis. In conclusion, epidemiological data of childhood vasculitis are useful both to health decision-making and to identify research priorities.
本研究旨在描述西班牙1997年至2011年儿童血管炎的住院负担,包括疾病类型、住院率和时间趋势。数据来自国家出院基本最小数据集(国家患者数据库)。分析了15岁以下儿童的住院事件。根据国际疾病分类第九版选择血管炎的主要诊断:大动脉炎、结节性多动脉炎、川崎病、韦格纳肉芽肿、变应性肉芽肿性血管炎和过敏性紫癜。1997年至2011年期间,西班牙共确定了14518例与血管炎相关的儿童住院病例。儿童的平均住院率为每10万人13.33±1.71例。过敏性紫癜和川崎病是最常见的血管炎类型,住院率分别为每10万名儿童11.00例和3.97例。其他血管炎在儿童期的住院情况则较为罕见。平均住院时间为6.04天,每例住院护理的估计费用为2847欧元。总体血管炎的医院病死率为0.05%。总之,儿童血管炎的流行病学数据对卫生决策和确定研究重点都很有用。