Granzow Jay W, Soderberg Julie M, Dauphine Christine
Harbor-UCLA Medical Center and the UCLA David Geffen School of Medicine, Los Angeles, California.
Breast J. 2014 Jul-Aug;20(4):420-2. doi: 10.1111/tbj.12282. Epub 2014 Jun 19.
Surgical treatment of chronic lymphedema has seen significant advances. Suction-assisted protein lipectomy (SAPL) has been shown to safely and effectively reduce the solid component of swelling in chronic lymphedema. However, these patients must continuously use compression garments to control and prevent recurrence. Microsurgery procedures, including lymphaticovenous anastomosis (LVA) and vascularized lymph node transfer (VLNT), have been shown to be effective in the management of the fluid component of lymphedema and allow for decreased garment use. SAPL and VLNT were applied together in a two-stage approach in two patients with chronic lymphedema after treatment for breast cancer. SAPL was used first to remove the chronic, solid component of the soft-tissue excess. Volume excess in our patients' arms was reduced an average of approximately 83% and 110% after SAPL surgery. After the arms had sufficiently healed and the volume reductions had stabilized, VLNT was performed to reduce the need for continuous compression and reduce fluid re-accumulation. Following the VLNT procedures, the patients were able to remove their compression garments consistently during the day and still maintain their volume reductions. Neither patient had any postoperative episodes of cellulitis. SAPL and VLNT can be combined to achieve optimal outcomes in patients with chronic lymphedema.
慢性淋巴水肿的外科治疗取得了显著进展。吸脂辅助蛋白脂肪切除术(SAPL)已被证明能安全有效地减少慢性淋巴水肿肿胀的固体成分。然而,这些患者必须持续使用压力衣来控制和预防复发。显微外科手术,包括淋巴管静脉吻合术(LVA)和带血管蒂淋巴结转移术(VLNT),已被证明在治疗淋巴水肿的液体成分方面有效,并可减少压力衣的使用。在两名乳腺癌治疗后的慢性淋巴水肿患者中,采用两阶段方法联合应用了SAPL和VLNT。首先使用SAPL去除软组织多余的慢性固体成分。在进行SAPL手术后,我们患者手臂的多余体积平均减少了约83%和110%。在手臂充分愈合且体积减少稳定后,进行VLNT以减少持续加压的需求并减少液体重新积聚。在VLNT手术后,患者能够在白天持续脱下压力衣,并且仍能保持体积减少。两名患者均未出现术后蜂窝织炎发作。SAPL和VLNT联合应用可使慢性淋巴水肿患者获得最佳治疗效果。