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后路腰椎椎间融合术(PLIF)后椎间植骨的体积变化:一项前瞻性研究。

Volumetric change in interbody bone graft after posterior lumbar interbody fusion (PLIF): a prospective study.

作者信息

Ito Zenya, Imagama Shiro, Kanemura Tokumi, Satake Kotaro, Ando Kei, Kobayashi Kazuyoshi, Shinjo Ryuichi, Yagi Hideki, Hida Tetsuro, Ito Kenyu, Ishikawa Yoshimoto, Tsushima Mikito, Matsumoto Akiyuki, El Zahlawy Hany, Yamaguchi Hidetoshi, Matsuyama Yukihiro, Ishiguro Naoki

机构信息

Department of Orthopedic Surgery, Nagoya University School of Medicine, 65 Tsurumai Shyowa-ward, Nagoya, 466-8550, Aichi, Japan,

出版信息

Eur Spine J. 2014 Oct;23(10):2144-9. doi: 10.1007/s00586-014-3410-z. Epub 2014 Jun 19.

Abstract

PURPOSE

The purpose of this study is to quantify the change in the volume of the interbody bone graft after the PLIF and monitor the change over time for subsequent analysis.

METHODS

The 114 cases were selected as the subjects of this study. The observation period was for 5 years following the surgery. The volume of the bone graft in the interbody space was calculated by summing up the cross-sectional area of the bone graft on each axial image multiplied by the height (2 mm) (the volume of the two cages was excluded). The volume ratio (%) = (bone graft volume)/(total volume of the interbody space - cage volume) was used for the purpose of evaluation.

RESULTS

The volumetric change of the bone graft was 51 % (3 months), 53 % (6 months), 54 % (1 year), 55 % (2 years), 59 % (3 years), 62 % (4 years), and 72 % (5 years), indicating a continued increase up to the 5-year mark. In particular, a significant increase was observed from the second year as compared with the previous years' result. Additionally, the volumetric increase from the second year to the fifth year was significantly higher than that before the second year.

CONCLUSIONS

The post-PLIF volumes of interbody bone grafts exhibited increases particularly from the second to fifth years after the procedure. Even the elderly and those with poor bone qualities can expect to have volumetric increases over time. Sufficient interbody space should be secured for accommodating bone grafts by intraoperative reduction, wherever possible.

摘要

目的

本研究的目的是量化后路腰椎椎间融合术(PLIF)后椎间植骨体积的变化,并监测其随时间的变化以便后续分析。

方法

选取114例患者作为本研究对象。观察期为术后5年。椎间植骨体积通过将每个轴向图像上植骨的横截面积乘以高度(2毫米)(不包括两个椎间融合器的体积)计算得出。采用体积比(%)=(植骨体积)/(椎间间隙总体积 - 融合器体积)进行评估。

结果

植骨的体积变化分别为:术后3个月51%,6个月53%,1年54%,2年55%,3年59%,4年62%,5年72%,表明直至5年时仍持续增加。特别是,与前几年相比,从第二年开始观察到显著增加。此外,从第二年到第五年的体积增加显著高于第二年之前。

结论

PLIF术后椎间植骨体积尤其在术后第二年至第五年呈现增加。即使是老年人和骨质较差者也有望随着时间推移实现体积增加。术中应尽可能通过复位确保有足够的椎间间隙以容纳植骨。

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