Xu Liwei, Ding Guoqing
Department of Urology, Sir Run Run Shaw Hospital, College of Medical Sciences, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China.
Oncol Lett. 2014 Apr;7(4):1144-1146. doi: 10.3892/ol.2014.1862. Epub 2014 Feb 7.
Haemangiopericytoma (HPC) is a rare soft-tissue tumour with great histological variability and unpredictable clinical and biological behaviour. HPC of the bladder is exceedingly rare and carries uncertain malignant potential. The current study reports a case of HPC of the bladder in a 48-year-old female, who was admitted to the Sir Run Run Shaw Hospital (Hangzhou, China) due to a large bladder mass. The patient exhibited no mass-related symptoms, such as pain, gross haematuria or urinary irritation. Seven years prior to admission, the patient underwent surgical resection of a bladder mass, which was determined to be HPC. Computed tomography scans showed a well-defined, heterogeneously enhancing solid cystic mass in the bladder. The patient underwent complete excision of the tumour and a partial cystectomy. The histopathological diagnosis was HPC of the bladder. The post-operative recovery was uneventful and no evidence of recurrence or metastasis was identified during two years of follow-up. The clinical and histological features, and the treatment and prognosis of this tumour are discussed together in the present study, with a review of the literature.
血管外皮细胞瘤(HPC)是一种罕见的软组织肿瘤,组织学表现高度变异,临床和生物学行为难以预测。膀胱血管外皮细胞瘤极为罕见,其恶性潜能尚不明确。本研究报告了一例48岁女性膀胱血管外皮细胞瘤病例,该患者因膀胱巨大肿块入住浙江大学医学院附属邵逸夫医院(中国杭州)。患者未出现与肿块相关的症状,如疼痛、肉眼血尿或尿路刺激症状。入院前七年,患者接受了膀胱肿块手术切除,术后病理确诊为血管外皮细胞瘤。计算机断层扫描显示膀胱内有一个边界清晰、强化不均匀的实性囊性肿块。患者接受了肿瘤完整切除及部分膀胱切除术。组织病理学诊断为膀胱血管外皮细胞瘤。术后恢复顺利,随访两年未发现复发或转移迹象。本研究结合文献复习,对该肿瘤的临床和组织学特征、治疗及预后进行了讨论。