与慢性丙型肝炎病毒相关的单侧痣样毛细血管扩张综合征（UNTS）及血管内皮生长因子（VEGF）免疫反应阳性。

Unilateral nevoid telangiectasia syndrome (UNTS) associated with chronic hepatitis C virus and positive immunoreactivity for VEGF.

作者信息

Smith J A, Kamangar F, Prakash N, Fung M A, Konia T, Fazel N

机构信息

University of California, Davis.

出版信息

Dermatol Online J. 2014 Jun 15;20(6):13030/qt8g9268sf.

PMID:24945644

Abstract

Unilateral Nevoid Telangectasia Syndrome (UNTS) is characterized by superficial telangiectasias in a unilateral distribution. Vascular endothelial growth factor (VEGF) may play a role in the pathogenesis of UNTS in patients with underlying hepatic disease. We report a case of a patient with UNTS accompanied by chronic hepatitis C virus infection, with a normal serum estrogen profile and strong positive immunohistochemical staining of lesional skin with VEGF.

摘要

单侧痣样毛细血管扩张综合征（UNTS）的特征是单侧分布的浅表毛细血管扩张。血管内皮生长因子（VEGF）可能在患有潜在肝脏疾病的UNTS患者的发病机制中起作用。我们报告一例伴有慢性丙型肝炎病毒感染的UNTS患者，其血清雌激素水平正常，病变皮肤VEGF免疫组化染色呈强阳性。