Tamborenea Maria N, Pisoni Cecilia, Toloza Sergio, Mysler Eduardo, Tate Guillermo, Pereira Dora, García Carrasco M, Quintero J, Cappuccio A, Granel A, Lazaro M, Arturi Pablo, Citera Gustavo, Velazco Zamora J, Saurit Veronica, Alvarellos A, Pons Estel S B, Danielsen C, Graf C, Paira Sergio, Ceccatto F, Cavallasca Javier, Civit E, Moreno J, Estevez A, Diaz M, Verando Marcela, Catalan Pellet Antonio, Gomez G, Maid Pablo, Beron Ana, Salvatierra Gabriela, Mendez Marcos, Cusa A, Rillo Oscar, Paez M, Larraude M, Sohn D, Gallo M, Conforti A, Malah Veronica, Tate Patricio, Baños A
Reumatologia, Organizacion Medica de Investigacion. Servicio Nacional de Rehabilitacion, Buenos Aires, Argentina,
Rheumatol Int. 2015 Jan;35(1):107-14. doi: 10.1007/s00296-014-3062-7. Epub 2014 Jun 20.
To determine the prevalence of and associated factors to work instability (WI) in rheumatoid arthritis (RA) Argentinean patients. Observational cross-sectional study that assessing employment status in currently working RA patients. They answered the validated version of RA work instability scale (RA-WIS). High-risk WI was considered when RA-WIS was ≥17. Factors associated with high-risk WI were examined by univariable and multivariable analysis. Four-hundred and fifty RA patients were enrolled; of these, 205 patients were currently employed, but only 172 have completed questionnaires required [RA-WIS and health assessment questionnaire (HAQ-A)]. Their mean age was 49.3 ± 10.8 years; 81.3 % were female; and their mean disease duration was 8.1 ± 7.2 years. Fifty-two percent of patients were doing manual work. The mean RA-WIS score was 11.4 ± 6.8, and 41 % of patients had a high-risk WI. High-risk WI was associated with radiographic erosions (p < 0.001) and HAQ-A >0.87 (p < 0.001) in the univariable analysis, whereas in the multivariable logistic regression analysis the variables associated with a high-risk WI were as follows: HAQ-A >0.87 [odds ratio (OR) 12.31; 95 % CI 5.38-28.18] and the presence of radiographic erosions (OR 4.848; 95 % CI 2.22-10.5). In this model, having a higher monthly income (OR 0.301; 95 % CI 0.096-0.943) and a better functional class (OR 0.151; 95 % CI 0.036-0.632) were protective. Forty-one percent of RA working patients had high-risk WI. The predictors of high RA-WIS were HAQ-A ≥0.87 and radiographic erosions, whereas having a better functional class and have higher incomes were protective.
确定阿根廷类风湿关节炎（RA）患者工作不稳定（WI）的患病率及相关因素。进行观察性横断面研究，评估目前正在工作的RA患者的就业状况。他们回答了经过验证的RA工作不稳定量表（RA-WIS）。当RA-WIS≥17时，被认为是高风险WI。通过单变量和多变量分析检查与高风险WI相关的因素。共纳入450例RA患者；其中，205例患者目前正在工作，但只有172例完成了所需问卷[RA-WIS和健康评估问卷（HAQ-A）]。他们的平均年龄为49.3±10.8岁；81.3%为女性；平均病程为8.1±7.2年。52%的患者从事体力劳动。RA-WIS平均得分为11.4±6.8，41%的患者有高风险WI。在单变量分析中，高风险WI与影像学侵蚀（p<0.001）和HAQ-A>0.87（p<0.001）相关，而在多变量逻辑回归分析中，与高风险WI相关的变量如下：HAQ-A>0.87[比值比（OR）12.31；95%置信区间5.38-28.18]和影像学侵蚀的存在（OR 4.848；95%置信区间2.22-10.5）。在该模型中，月收入较高（OR 0.301；95%置信区间0.096-0.943）和功能等级较好（OR 0.151；95%置信区间0.036-0.632）具有保护作用。41%的RA在职患者有高风险WI。RA-WIS高的预测因素是HAQ-A≥0.87和影像学侵蚀，而功能等级较好和收入较高具有保护作用。
