基于离子和非离子成分的半互穿网络水凝胶的溶胀行为和形态学特性

Swelling behavior and morphological properties of semi-IPN hydrogels based on ionic and non-ionic components.

作者信息

Pulat Mehlika, Ozgündüz Hediye İrem

机构信息

Gazi Universitesi, Fen Fakültesi, Kimya Bölümü, Ankara, Turkey.

出版信息

Biomed Mater Eng. 2014;24(4):1725-33. doi: 10.3233/BME-140984.

DOI:10.3233/BME-140984

PMID:24948456

Abstract

Semi-interpenetrating polymer network (IPN) hydrogels with different compositions of poly(vinyl alcohol) (PVA), poly(acrylic acid) (PAA) and poly(acrylamide) (PAAm) were synthesized via free radical polymerization using ethylene glycol dimethacrylate (EGDMA) as crosslinker. The variations of swelling percentages (S%) with time, temperature and pH were determined for all hydrogels. Average S% values at pH=7.4 and 37°C were determined to be 1660% for PAA/PVA, the most swollen hydrogel, and 550% for PAAm/PVA, the least swollen IPN-hydrogel. Swelling behaviors based on ionic and non-ionic components were also explained with detailed SEM micrographs of the hydrogels.

摘要

以乙二醇二甲基丙烯酸酯（EGDMA）为交联剂，通过自由基聚合反应合成了具有不同聚乙烯醇（PVA）、聚丙烯酸（PAA）和聚丙烯酰胺（PAAm）组成的半互穿聚合物网络（IPN）水凝胶。测定了所有水凝胶的溶胀率（S%）随时间、温度和pH值的变化。对于最易溶胀的水凝胶PAA/PVA，在pH = 7.4和37°C时的平均S%值为1660%，而对于最不易溶胀的IPN水凝胶PAAm/PVA，该值为550%。还通过水凝胶的详细扫描电子显微镜图像解释了基于离子和非离子成分的溶胀行为。