Francis Jasmine H, Xu Xiaoliang L, Gobin Y Pierre, Marr Brian P, Brodie Scott E, Abramson David H
Ophthalmic Oncology Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Open Ophthalmol J. 2014 May 16;8:7-11. doi: 10.2174/1874364101408010007. eCollection 2014.
There is growing interest in intravitreal injections of chemotherapy for retinoblastoma. However, concerns for potential tumor seeding through the needle track has prompted the use of risk-reducing precautionary methods. Presented here is a novel technique, which can be easily replicated, requires minimal sophisticated equipment and with laboratory data supporting its concept. Sterile distilled water submersion for 3 minutes renders retinoblastoma cells nonviable and can be employed as a precautionary method following intravitreal injection in the technique described here.
玻璃体内注射化疗药物治疗视网膜母细胞瘤越来越受到关注。然而，对通过针道潜在肿瘤播散的担忧促使人们采用降低风险的预防方法。本文介绍了一种新技术，该技术易于复制，所需精密设备最少，且有实验室数据支持其理念。无菌蒸馏水浸泡3分钟可使视网膜母细胞瘤细胞失去活性，在此处描述的技术中，可在玻璃体内注射后用作一种预防方法。
