Nakano E, Iwasaki A, Seguchi T, Sugao H, Yoshioka T, Tada Y, Matsuda M, Sonoda T
Dept. of Urology, Osaka University Hospital.
Gan To Kagaku Ryoho. 1989 Mar;16(3 Pt 1):415-7.
We report a case in which para-aortic lymphnode metastasis from bladder cancer regressed completely by administration of UFT. The patient was a 72-year-old male who had undergone a total cystectomy for bladder cancer. Since para-aortic node metastasis was recognized in abdominal CT 1 year after the operation, we treated this patient by oral administration of UFT at a dose of 600 mg per day, and the metastatic lesion regressed completely 2 months later. After the complete regression, UFT was administered for one year. At present, 6 months after the discontinuation of UFT, para-aortic lymphnode swelling is not observed. Although adverse effects such as pigmentation and nail degeneration was found, there was no abnormal finding in blood analysis and chemistry. It is suggested that UFT may be effectively used for bladder cancer.
我们报告了一例膀胱癌腹主动脉旁淋巴结转移通过服用优福定(UFT)而完全消退的病例。该患者为一名72岁男性,因膀胱癌接受了全膀胱切除术。术后1年腹部CT检查发现腹主动脉旁淋巴结转移,我们对该患者采用口服优福定治疗,剂量为每日600毫克,2个月后转移病灶完全消退。完全消退后,继续服用优福定1年。目前,停用优福定6个月后,未观察到腹主动脉旁淋巴结肿大。虽然发现有色素沉着和指甲变性等不良反应,但血液分析和生化检查未发现异常。提示优福定可能对膀胱癌有效。