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高海拔地区的认知障碍与适应。

Cognitive impairments at high altitudes and adaptation.

机构信息

New York University School of Medicine , New York, New York.

出版信息

High Alt Med Biol. 2014 Jun;15(2):141-5. doi: 10.1089/ham.2014.1009. Epub 2014 Jun 20.

DOI:10.1089/ham.2014.1009
PMID:24949527
Abstract

High altitude hypoxia has been shown to have significant impact on cognitive performance. This article reviews the aspects in which, and the conditions under which, decreased cognitive performance has been observed at high altitudes. Neural changes related to high altitude hypoxia are also reviewed with respect to their possible contributions to cognitive impairments. In addition, potential adaptation mechanisms are reviewed among indigenous high altitude residents and long-term immigrant residents, with discussions about methodological concerns related to these studies.

摘要

高海拔低氧已被证明对认知表现有重大影响。本文综述了在高海拔环境下观察到认知表现下降的方面和条件。还综述了与高海拔低氧相关的神经变化及其对认知障碍的可能贡献。此外,还综述了高原世居者和长期移居者的潜在适应机制,并讨论了这些研究中与方法相关的关注点。

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