Lymphocyte Development Group, MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK.
Immunity. 2014 Jun 19;40(6):855-6. doi: 10.1016/j.immuni.2014.06.004.
In this issue of Immunity, Escobar et al. (2014) bring microRNAs and chromatin together by showing how activation-induced miR-155 targets the chromatin protein Jarid2 to regulate proinflammatory cytokine production in T helper 17 cells.
在本期《免疫》中,Escobar 等人(2014)通过展示激活诱导的 miR-155 如何靶向染色质蛋白 Jarid2 来调节辅助性 T 细胞 17 细胞中促炎细胞因子的产生,将 microRNAs 和染色质联系在一起。