Suzuki Saeko, Kaga Akimune, Kusaka Natsuko, Uematsu Mitsugu, Haginoya Kazuhiro, Katata Yu, Matsubara Yoko, Ishida Tomoyuki, Kitaoka Setsuko, Kumaki Satoru
Department of Pediatrics, Sendai Medical Center, Sendai, Miyagi, Japan.
Department of Pediatrics, Tohoku University School of Medicine, Sendai, Miyagi, Japan.
Pediatr Neurol. 2014 Aug;51(2):279-81. doi: 10.1016/j.pediatrneurol.2014.05.002. Epub 2014 May 9.
Acute cerebellitis with unilateral onset is rare, and magnetic resonance imaging (MRI) is a useful method for demonstrating cerebellar involvement.
We report a 12-year-old girl with acute cerebellitis with a unique sequential change on her MRI.
The patient's brain MRI first revealed cortical lesions mainly in the right cerebellar hemisphere. These subsequently disappeared, and at the same time, new lesions appeared in the opposite cerebellar hemisphere. All the lesions were confined to gray matter in the cerebellum and were isotense on diffusion-weighted imaging and had high signal intensity on the apparent diffusion coefficient map, consistent with the characteristic of vasogenic edema.
The sequential MRI demonstrates conversion of hemicerebellitis to bilateral cerebellitis during subacute phase, and vasogenic edema might be contributing to the pathogenesis of acute cerebellitis in this patient.
单侧起病的急性小脑炎较为罕见,磁共振成像(MRI)是显示小脑受累的有用方法。
我们报告一名12岁女孩患有急性小脑炎,其MRI有独特的序列变化。
患者的脑部MRI最初显示主要位于右侧小脑半球的皮质病变。这些病变随后消失,与此同时,对侧小脑半球出现新的病变。所有病变均局限于小脑灰质,在扩散加权成像上呈等密度,在表观扩散系数图上呈高信号强度,符合血管源性水肿的特征。
序列MRI显示在亚急性期半侧小脑炎转变为双侧小脑炎,血管源性水肿可能是该患者急性小脑炎发病机制的原因。