胰十二指肠切除术后并发症定义及检索方法的差异影响结果统计:NSQIP与非NSQIP方法的比较

Variations in definition and method of retrieval of complications influence outcomes statistics after pancreatoduodenectomy: comparison of NSQIP with non-NSQIP methods.

作者信息

Sanford Dominic E, Woolsey Cheryl A, Hall Bruce L, Linehan David C, Hawkins William G, Fields Ryan C, Strasberg Steven M

机构信息

Section of Hepato-Pancreato-Biliary Surgery, Washington University in St Louis, and Barnes-Jewish Hospital, St Louis, MO.

Washington University in St Louis Department of Surgery, Olin Business School, and Center for Health Policy; St Louis VA Medical Center; BJC Healthcare Saint Louis, St Louis, MO.

出版信息

J Am Coll Surg. 2014 Sep;219(3):407-15. doi: 10.1016/j.jamcollsurg.2014.01.064. Epub 2014 Apr 18.

Abstract

BACKGROUND

NSQIP and the Accordion Severity Grading System have recently been used to develop quantitative methods for measuring the burden of postoperative complications. However, other audit methods such as chart reviews and prospective institutional databases are commonly used to gather postoperative complications. The purpose of this study was to evaluate discordance between different audit methods in pancreatoduodenectomy--a common major surgical procedure. The chief aim was to determine how these different methods could affect quantitative evaluations of postoperative complications.

STUDY DESIGN

Three common audit methods were compared with NSQIP in 84 patients who underwent pancreatoduodenectomy. The methods were use of a prospective database, a chart review based on discharge summaries only, and a detailed retrospective chart review. The methods were evaluated for discordance with NSQIP and among themselves. Severity grading was performed using the Modified Accordion System.

RESULTS

Fifty-three complications were listed by NSQIP and 31 complications were identified that were not listed by NSQIP. There was poor agreement for NSQIP-type complications between NSQIP and the other audit methods for mild and moderate complications (kappa 0.381 to 0.744), but excellent agreement for severe complications (kappa 0.953 to 1.00). Discordance was usually due to variations in definition of the complications in non-NSQIP methods. There was good agreement among non-NSQIP methods for non-NSQIP complications for moderate and severe complications, but not for mild complications.

CONCLUSIONS

There are important differences in perceived surgical outcomes based on the method of complication retrieval. The non-NSQIP methods used in this study could not be substituted for NSQIP in a quantitative analysis unless that analysis was limited to severe complications.

摘要

背景

国家外科质量改进计划(NSQIP)和手风琴严重程度分级系统最近被用于开发测量术后并发症负担的定量方法。然而,其他审计方法,如图表审查和前瞻性机构数据库,通常用于收集术后并发症。本研究的目的是评估胰十二指肠切除术(一种常见的大型外科手术)中不同审计方法之间的不一致性。主要目的是确定这些不同方法如何影响术后并发症的定量评估。

研究设计

在84例行胰十二指肠切除术的患者中,将三种常见的审计方法与NSQIP进行比较。这些方法包括使用前瞻性数据库、仅基于出院小结的图表审查以及详细的回顾性图表审查。评估这些方法与NSQIP之间以及它们自身之间的不一致性。使用改良手风琴系统进行严重程度分级。

结果

NSQIP列出了53例并发症,另外还识别出31例NSQIP未列出的并发症。对于轻度和中度并发症,NSQIP与其他审计方法在NSQIP型并发症方面的一致性较差(kappa值为0.381至0.744),但对于严重并发症一致性极佳(kappa值为0.953至1.00)。不一致通常是由于非NSQIP方法中并发症定义的差异。对于中度和重度非NSQIP并发症,非NSQIP方法之间一致性良好,但对于轻度并发症则不然。

结论

基于并发症检索方法,在感知的手术结果方面存在重要差异。本研究中使用的非NSQIP方法在定量分析中不能替代NSQIP,除非该分析仅限于严重并发症。

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