Department of Psychology, University of California, Berkeley, USA; Department of Psychiatry, University of Pittsburgh Medical Center, USA.
Department of Psychiatry & Behavioral Science, Stanford University Medical Center, USA.
J Affect Disord. 2014;167:93-7. doi: 10.1016/j.jad.2014.05.060. Epub 2014 Jun 6.
The aim was to examine the prevalence and consequences of co-occurring insomnia and hypersomnia symptoms in depressed adults drawn from a representative sample of the U.S. population.
Data from 687 National Comorbidity Survey Replication (NCS-R) respondents meeting criteria for a major depressive episode (MDE) in the past year were included. Respondents completed clinical interviews that assessed 12-month DSM-IV disorders, impairment, mental health treatment, and depressive symptom severity. Outcomes were compared between respondents who experienced insomnia symptoms-only (N=404), hypersomnia symptoms-only (N=44), both insomnia and hypersomnia symptoms (N=184) and no sleep problems (N=55) during an MDE.
Insomnia and hypersomnia symptoms co-occurred in 27.7% of respondents with past-year MDEs, most frequently in bipolar spectrum disorders and major depressive disorder with dysthymia. Similar to the insomnia-only group, respondents with co-occurring sleep disturbances had more severe depression, and higher rates of past-year impulse control disorders and suicide planning. Similar to the hypersomnia-only group, respondents with co-occurring sleep disturbances had higher rates of past-year drug use disorders and suicide attempts. Compared to the insomnia-only and no sleep problem groups, respondents with both sleep disturbances were more frequently in mental health treatment, seeing a general practitioner, and taking antidepressants.
The NCS-R is cross-sectional and did not evaluate sleep disorder diagnoses.
Co-occurring insomnia and hypersomnia symptoms were associated with a more severe MDE. Further research is warranted to more fully understand the joint presentation of insomnia and hypersomnia in depression.
本研究旨在调查美国代表性人群中患有抑郁症的成年人中同时存在失眠和嗜睡症状的患病率及其后果。
本研究纳入了符合过去一年中患有重度抑郁发作(MDE)标准的 687 名来自国家共病调查-再调查(NCS-R)的受访者的数据。受访者完成了临床访谈,评估了 12 个月内 DSM-IV 障碍、损伤、心理健康治疗和抑郁症状严重程度。将在 MDE 期间经历失眠症状仅(N=404)、嗜睡症状仅(N=44)、同时存在失眠和嗜睡症状(N=184)和无睡眠问题(N=55)的受访者的结果进行了比较。
在过去一年患有 MDE 的受访者中,27.7%同时存在失眠和嗜睡症状,最常见于双相谱系障碍和伴有恶劣心境的重度抑郁障碍。与失眠仅组相似,同时存在睡眠障碍的受访者抑郁程度更严重,且过去一年中冲动控制障碍和自杀计划的发生率更高。与嗜睡仅组相似,同时存在睡眠障碍的受访者过去一年中药物使用障碍和自杀未遂的发生率更高。与失眠仅组和无睡眠问题组相比,同时存在两种睡眠障碍的受访者更频繁地接受心理健康治疗,看全科医生,服用抗抑郁药。
NCS-R 是横断面研究,未评估睡眠障碍诊断。
同时存在失眠和嗜睡症状与更严重的 MDE 相关。需要进一步研究以更全面地了解抑郁中失眠和嗜睡的联合表现。