Bertelsen Mette, Linneberg Allan, Rosenberg Thomas
Kennedy Center Eye Clinic, Glostrup Hospital, Glostrup, Denmark; Department of Ophthalmology, Glostrup Hospital, Glostrup, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Acta Ophthalmol. 2015 Mar;93(2):134-40. doi: 10.1111/aos.12467. Epub 2014 Jun 22.
To examine socio-economic characteristics of patients with generalized retinal dystrophy in Denmark.
Cross-sectional population-based study with analysis of socio-economic characteristics including income, education, employment status and civil status in 2285 patients from the Danish Retinitis Pigmentosa Registry and 228,500 control subjects matched by age and gender. Demographic and socio-economic data were retrieved from Statistics Denmark. Differences between cases and controls were estimated using conditional logistic regression.
On 1 January 2012, 2285 patients with a Danish civil registration number were registered as having a generalized retinal dystrophy. At the age of 40 years, less patients than controls had a high education (odds ratio (OR), 0.51; 95% confidence interval (CI95), 0.41-0.62), a high income (OR, 0.21; CI95, 0.17-0.26) and were married (OR, 0.39; CI95, 0.33-0.45). More patients than controls were pensioners (OR, 6.04; CI95, 5.23-6.97).
We found that patients with generalized retinal dystrophy differed significantly from a matched control group on several socio-economic characteristics. The differences were more pronounced in patients with systemic involvement and patients with an early age at disease presentation. The socio-economic inequalities of this group of blinding diseases emphasize the importance of rehabilitation and need for a substantial and multidisciplinary support from the healthcare, educational and social systems.
研究丹麦广泛性视网膜营养不良患者的社会经济特征。
基于人群的横断面研究，分析丹麦视网膜色素变性登记处的2285例患者以及按年龄和性别匹配的228,500名对照者的社会经济特征，包括收入、教育程度、就业状况和婚姻状况。人口统计学和社会经济数据取自丹麦统计局。使用条件逻辑回归估计病例组和对照组之间的差异。
2012年1月1日，2285名拥有丹麦民事登记号码的患者被登记为患有广泛性视网膜营养不良。在40岁时，与对照组相比，患者中接受高等教育的人数较少（优势比（OR）为0.51；95%置信区间（CI95）为0.41 - 0.62），高收入者较少（OR为0.21；CI95为0.17 - 0.26），已婚者较少（OR为0.39；CI95为0.33 - 0.45）。与对照组相比，患者中领取养老金者更多（OR为6.04；CI95为5.23 - 6.97）。
我们发现广泛性视网膜营养不良患者在几个社会经济特征方面与匹配的对照组有显著差异。这些差异在有全身受累的患者和疾病发病年龄较早的患者中更为明显。这组致盲疾病的社会经济不平等凸显了康复的重要性以及医疗、教育和社会系统提供大量多学科支持的必要性。
