Čoga Lucija, Masiero Stefano, Drevenšek-Olenik Irena
Faculty of Mathematics and Physics, University of Ljubljana, Jadranska 19, SI-1000 Ljubljana, Slovenia.
Alma Mater Studiorum - Università di Bologna, Dipartimento di Chimica Organica "A. Mangini", Via San Giacomo 11, I-40126 Bologna, Italy.
Colloids Surf B Biointerfaces. 2014 Sep 1;121:114-21. doi: 10.1016/j.colsurfb.2014.05.038. Epub 2014 Jun 4.
We performed a comparative study on the self-assembling properties of four guanosine derivatives with one and two lipophilic chains of two different lengths at the air-water interface and after Langmuir-Blodgett (LB) deposition onto various solid supports (mica, silicon wafer, graphite). At the air-water interface the derivatives with one lipophilic chain exhibit surface compression behaviour with a profound first order phase transition from the liquid-expanded to the liquid-condensed phase. They assemble into lamellar surface formations, whose structural characteristics remain practically unmodified after their transfer onto the solid substrates. Domain regions with orientationally aligned lamellar formations of sizes up to 150μm(2) can be obtained. The compression behaviour of double-chain derivatives is more diverse. While the derivative with two decanoyl chains exhibits the liquid-expanded as well as the liquid-condensed phase, the derivative with two hexadecanoyl chains reveals only the condensed-analogous phase with a relatively high collapse pressure. LB films of double chain derivatives show formation of very homogeneous and compact surface structures with high surface coverage.
我们对四种鸟苷衍生物进行了一项比较研究，这些衍生物分别带有一条和两条不同长度的亲脂性链，研究其在空气-水界面以及通过朗缪尔-布洛杰特（LB）沉积到各种固体支持物（云母、硅片、石墨）上后的自组装特性。在空气-水界面，带有一条亲脂性链的衍生物表现出表面压缩行为，具有从液体扩张相到液体凝聚相的明显一级相变。它们组装成层状表面结构，转移到固体基质上后其结构特征基本保持不变。可以获得尺寸达150μm(2)的具有定向排列层状结构的畴区。双链衍生物的压缩行为更为多样。带有两条癸酰基链的衍生物表现出液体扩张相以及液体凝聚相，而带有两条十六酰基链的衍生物仅显示出具有相对较高崩塌压力的类似凝聚相。双链衍生物的LB膜显示形成了具有高表面覆盖率的非常均匀且致密的表面结构。
