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儿童和青年的罗斯手术:来自英国国家数据库的12年结果与趋势

The Ross Operation in Children and Young Adults: 12-Year Results and Trends From the UK National Database.

作者信息

Zebele Carlo, Chivasso Pierpaolo, Sedmakov Christo, Angelini Gianni, Caputo Massimo, Parry Andrew, Stoica Serban

机构信息

Children's Hospital, University Hospitals Bristol NHS Trust, Bristol, United Kingdom.

Children's Hospital, University Hospitals Bristol NHS Trust, Bristol, United Kingdom Imperial College, London, United Kingdom.

出版信息

World J Pediatr Congenit Heart Surg. 2014 Jul;5(3):406-12. doi: 10.1177/2150135114537532.

Abstract

OBJECTIVES

To determine UK national trends and results of the Ross operation in relation to all aortic valve interventions.

METHODS

Examination of the UK Congenital Central Cardiac Audit Database for all aortic valve procedures performed between 2000 and 2011 in children (0-16 years) and young adults (16-30 years).

RESULTS

A total of 2,206 aortic valve procedures were performed in children and 1,824 in young adults, the proportions in the two groups being: Ross operation (19% vs 15%, respectively), surgical valvoplasty (9.5% vs 4%), surgical valvotomy (9.5% vs 1%), aortic valve replacement (AVR; 11% vs 55%), aortic root replacement (4% vs 18%), and balloon valvoplasty (47% vs 7%). The 30-day and 1-year survival after Ross is 99.3% and 98.7%, respectively, in the last four years achieving 100%. In children, the proportion of balloon valvoplasty increased from an average of 43% in 2000 to 2006 to 53% in 2007 to 2011, whereas the Ross operation decreased from 22% to 16% (P < .001). In young adults, the figures are an increase from 49% to 58% for AVR compared to a decrease from 23% to 9% for Ross (P < .001). Our own single-center series of 91 patients also shows standard results for early- and long-term survival and freedom from reoperation, but gradually fewer Ross operations performed. The year-on-year changes show a significant decreasing trend locally and nationally.

CONCLUSIONS

Despite an excellent track record, the Ross operation is performed less frequently in the United Kingdom. This report is a first step in comparing treatment modalities at national level.

摘要

目的

确定在所有主动脉瓣干预措施中,罗斯手术在英国的全国趋势和结果。

方法

检查英国先天性心脏中心审计数据库中2000年至2011年间对儿童(0至16岁)和年轻人(16至30岁)实施的所有主动脉瓣手术。

结果

儿童共进行了2206例主动脉瓣手术,年轻人进行了1824例,两组中的比例分别为:罗斯手术(分别为19%和15%)、外科瓣膜成形术(9.5%和4%)、外科瓣膜切开术(9.5%和1%)、主动脉瓣置换术(AVR;11%和55%)、主动脉根部置换术(4%和18%)以及球囊瓣膜成形术(47%和7%)。在过去四年中,罗斯手术后30天和1年生存率分别为99.3%和98.7%,最近四年达到100%。在儿童中,球囊瓣膜成形术的比例从2000年至2006年的平均43%增加到2007年至2011年的53%,而罗斯手术从22%降至16%(P < 0.001)。在年轻人中,AVR的比例从49%增加到58%,而罗斯手术从23%降至9%(P < 0.001)。我们自己单中心的91例患者系列也显示了早期和长期生存以及再次手术率方面的标准结果,但罗斯手术的实施逐渐减少。逐年变化显示在本地和全国范围内均有显著下降趋势。

结论

尽管罗斯手术有着出色的记录,但在英国实施的频率较低。本报告是在国家层面比较治疗方式的第一步。

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