de Andrade Sousa Alexandre, Lopes Rena Rafael, Souza Silva Guilherme, Marcos Arantes Soares João, Porcaro-Salles José Maria, Nunes Laiz, Alves Mesquita Ricardo, Jham Bruno Correia
Instituto Alfa de Gastroenterologia, Federal University of Minas Gerais, Brazil.
Instituto Alfa de Gastroenterologia, Federal University of Minas Gerais, Brazil; School of Medicine, Federal University of Sao Joao Del Rey, Brazil.
J Craniomaxillofac Surg. 2014 Oct;42(7):1536-9. doi: 10.1016/j.jcms.2014.04.026. Epub 2014 May 9.
Spontaneous remission is a rare, but well recognized event in oncology. Certain tumours, such as melanomas, hypernephromas and neuroblastomas, are known for showing spontaneous regression. Similarly, spontaneous regression of oral lymphomas, as well as oropharyngeal and recurrent tongue carcinomas, has been reported. Here, we present a novel case of a patient with a primary squamous cell carcinoma on the floor of the mouth whose tumour regressed spontaneously in three months, without any treatment. We also review of the literature on the spontaneous remission of oral cancer and discuss possible mechanisms for this phenomenon.
自发缓解在肿瘤学中是一种罕见但已得到充分认识的现象。某些肿瘤，如黑色素瘤、肾细胞癌和神经母细胞瘤，以出现自发消退而闻名。同样，口腔淋巴瘤以及口咽癌和复发性舌癌的自发消退也有报道。在此，我们报告一例罕见病例，一名原发性口底鳞状细胞癌患者的肿瘤在未经任何治疗的情况下于三个月内自发消退。我们还回顾了关于口腔癌自发缓解的文献，并讨论了这种现象可能的机制。
