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双相情感障碍青少年的治疗模式:来自全国共病调查青少年补充调查(NCS-A)的结果。

Treatment patterns of youth with bipolar disorder: results from the National Comorbidity Survey-Adolescent Supplement (NCS-A).

作者信息

Khazanov Gabriela Kattan, Cui Lihong, Merikangas Kathleen Ries, Angst Jules

机构信息

Genetic Epidemiology Research Branch, National Institute of Mental Health, Bldg. 35A, Rm 2E410, 35 Convent Dr. MSC 3720, Bethesda, MD, 20892-0001, USA.

出版信息

J Abnorm Child Psychol. 2015 Feb;43(2):391-400. doi: 10.1007/s10802-014-9885-6.

Abstract

Despite growing evidence that bipolar disorder often emerges in adolescence, there are limited data regarding treatment patterns of youth with bipolar disorder in community samples. Our objective was to present the prevalence and clinical correlates of treatment utilization for a nationally representative sample of US adolescents with bipolar disorder. Analyses are based on data from the National Comorbidity Survey-Adolescent Supplement, a face-to-face survey of 10,123 adolescents (ages 13-18) identified in household and school settings. We found that of adolescents meeting DSM-IV criteria for bipolar I or II disorder (N = 250), 49 % were treated for depression or mania, 13 % were treated for conditions other than depression or mania, and 38 % did not report receiving treatment. Treatment for depression or mania was associated with increased rates of suicide attempts, as well as greater role disability and more comorbid alcohol use relative to those who had not received treatment. Treated adolescents had triple the rate of ADHD and double the rates of behavior disorders than those without treatment. Our findings demonstrate that a substantial proportion of youth with bipolar disorder do not receive treatment, and of those who do, many receive treatment for comorbid conditions rather than for their mood-related symptoms. Treatment was more common among youth with severe manifestations and consequences of bipolar disorder and those with behavior problems. These trends highlight the need to identify barriers to treatment for adolescents with bipolar disorder and demonstrate that those in treatment are not representative of youth with bipolar disorder in the general population.

摘要

尽管越来越多的证据表明双相情感障碍常在青少年期出现,但关于社区样本中双相情感障碍青少年的治疗模式的数据有限。我们的目标是呈现美国双相情感障碍青少年全国代表性样本的治疗利用率及其临床相关因素。分析基于全国共病调查青少年补充版的数据,这是一项对在家庭和学校环境中识别出的10123名青少年(年龄13 - 18岁)进行的面对面调查。我们发现,在符合双相I型或II型障碍DSM - IV标准的青少年(N = 250)中,49%接受了抑郁或躁狂治疗,13%接受了抑郁或躁狂以外疾病的治疗,38%未报告接受过治疗。与未接受治疗的青少年相比,抑郁或躁狂治疗与自杀未遂率增加、角色功能障碍加重以及酒精使用共病更多相关。接受治疗的青少年患注意缺陷多动障碍(ADHD)的比例是未治疗青少年的三倍,行为障碍的比例是未治疗青少年的两倍。我们的研究结果表明,相当一部分双相情感障碍青少年未接受治疗,而在接受治疗的青少年中,许多人是因共病情况而非与情绪相关的症状接受治疗。在双相情感障碍有严重表现和后果的青少年以及有行为问题的青少年中,治疗更为常见。这些趋势凸显了识别双相情感障碍青少年治疗障碍的必要性,并表明接受治疗的青少年并不代表一般人群中患有双相情感障碍的青少年。

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