Clugston Robin D, Blaner William S
Department of Medicine, Columbia University, New York, New York.
Zoo Biol. 2014 Nov-Dec;33(6):527-35. doi: 10.1002/zoo.21140. Epub 2014 Jun 24.
Vitamin A status is an important consideration in the health of both wild and captive amphibians. Data concerning whole body vitamin A homeostasis in amphibians are scarce, although these animals have been used as experimental models to study the actions of vitamin A in vision, limb regeneration and embryogenesis. The available data suggest that many aspects of vitamin A biology in amphibians are similar to the canonical characteristics of vitamin A metabolism and actions established in mammals. This is consistent with the evolutionary conservation of these important biological processes. Amphibians must obtain vitamin A in their diet, with captive animals being prone to vitamin A deficiency. There is still much to be learned about vitamin A biology in amphibians that can only be achieved through rigorous scientific research. Improved understanding of amphibian vitamin A biology will aid the conservation of endangered amphibians in the wild, as well as the successful maintenance of ex situ populations.
维生素A状况是野生和圈养两栖动物健康的一个重要考量因素。尽管两栖动物已被用作研究维生素A在视觉、肢体再生和胚胎发育中作用的实验模型，但有关两栖动物全身维生素A稳态的数据却很稀少。现有数据表明，两栖动物维生素A生物学的许多方面与哺乳动物中确立的维生素A代谢和作用的典型特征相似。这与这些重要生物过程的进化保守性是一致的。两栖动物必须从饮食中获取维生素A，圈养动物容易出现维生素A缺乏症。关于两栖动物维生素A生物学仍有许多有待了解的地方，这只有通过严谨的科学研究才能实现。更好地了解两栖动物维生素A生物学将有助于保护野生濒危两栖动物，以及成功维持圈养种群。
