Zhang Hengzhu, Zhang Nan, Dong Lun, She Lei, Wang Xiaodong, Xu Enxi, Yan Zhengcun, Zhang Xian
Department of Neurosurgery, Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu 225001, P.R. China.
Oncol Lett. 2014 Jul;8(1):281-284. doi: 10.3892/ol.2014.2074. Epub 2014 Apr 16.
The current study presents a case of a 43-year-old female with giant bilateral calvarial hyperostosis across the superior sagittal sinus, secondary to brain meningioma. The patient presented with a huge mass in the bilateral calvarial region, and diagnoses of huge skull hyperplasia and meningioma were strongly suggested by computed tomography and magnetic resonance imaging examination. In addition, digital subtraction angiography demonstrated that the left middle meningeal artery and branches of the left superficial temporal artery were the major sources of blood supply to the tumor, with the little involvement of the right middle meningeal artery and branches of the right superficial temporal artery. The patient successfully underwent simultaneous embolization of the tumor-supplying vessels, total resection of the giant calvarial hyperostosis and intracranial tumor and skull cranioplasty. Additionally, histological study of the mass revealed a meningioma. The management of such a case presents a surgical challenge, however, the current study provides a good reference for the future treatment of similar diseases.
本研究报告了一例43岁女性患者，患有横跨上矢状窦的双侧巨大颅骨增生，继发于脑海绵状血管瘤。患者双侧颅骨区域出现巨大肿块，计算机断层扫描和磁共振成像检查强烈提示巨大颅骨增生和海绵状血管瘤的诊断。此外，数字减影血管造影显示，左脑膜中动脉和左颞浅动脉分支是肿瘤的主要供血来源，右脑膜中动脉和右颞浅动脉分支受累较少。患者成功接受了肿瘤供血血管的同步栓塞、巨大颅骨增生和颅内肿瘤的全切除以及颅骨成形术。此外，对肿块的组织学研究显示为海绵状血管瘤。这种病例的治疗具有手术挑战性，然而，本研究为未来类似疾病的治疗提供了良好的参考。
