Wijekoon N, Samarasinghe M, Dalpatadu U, Nuzair N, Pratheepan P, Samarasekera D
University of Colombo, Sri Lanka.
J Surg Case Rep. 2012 Oct 1;2012(10):6. doi: 10.1093/jscr/2012.10.6.
Cronkhite-Canada syndrome is an extremely rare condition of gastrointestinal polyposis in which the main presenting features are diarrhoea and dysgeusia. The polyps in this condition are characteristically distributed throughout the entire gastrointestinal tract except the oesophagus, and these patients exhibit unique ectodermal abnormalities. Herein, we report a 50-year-old male who had recurrent episodes of severe haematochezia from the polyps in the colon. Further examination and investigations revealed a diagnosis of Cronkhite-Canada syndrome. Proctocolectomy was carried out for medically refractory haematochezia and the patient is asymptomatic at present.
克朗凯特-加拿大综合征是一种极为罕见的胃肠道息肉病,其主要表现为腹泻和味觉障碍。这种情况下的息肉典型地分布于除食管外的整个胃肠道,并且这些患者表现出独特的外胚层异常。在此,我们报告一名50岁男性,他因结肠息肉反复出现严重便血。进一步检查和调查后诊断为克朗凯特-加拿大综合征。因药物治疗难以控制便血而进行了直肠结肠切除术,患者目前无症状。