Thurm Audrey, Manwaring Stacy S, Swineford Lauren, Farmer Cristan
National Institute of Mental Health, Bethesda, MD, USA.
J Child Psychol Psychiatry. 2015 Jan;56(1):97-104. doi: 10.1111/jcpp.12285. Epub 2014 Jun 24.
A significant minority of children with autism spectrum disorder (ASD) are considered 'minimally verbal' due to language development stagnating at a few words. Recent developments allow for the severity of ASD symptoms to be examined using Autism Diagnostic Observation Schedule (ADOS) Social Affect (SA) and Restricted and Repetitive Behaviors (RRB) domain severity scores. The aim of the current study was to explore language outcomes in a cohort of minimally verbal children with autism evaluated through the preschool years and determine if and how ASD symptom severity in core domains predicts the development of spoken language by age 5.
The sample consisted of 70 children with autism aged 1-5 years at the first evaluation who were examined at least 1 year later, during their fifth year of age. The ADOS overall level of language item was used to categorize children as minimally verbal or having phrase speech, and the Mullen Scales of Early Learning was used as a continuous measure of expressive language.
At Time 1, 65% (n = 47) of children in the sample were minimally verbal and by Time 2, 36% (n = 17 of 47) of them had developed phrase speech. While the Time 1 ADOS calibrated severity scores did not predict whether or not a child remained minimally verbal at Time 2, change in the SA calibrated severity score (but not RRB) was predictive of the continuous measure of expressive language. However, change in SA severity no longer predicted continuous expressive language when nonverbal cognitive ability was added to the model.
Findings indicate that the severity of SA symptoms has some relationship with continuous language outcome, but not categorical. However, the omnipresent influence of nonverbal cognitive ability was confirmed in the current study, as the addition of it to the model rendered null the predictive utility of SA severity.
由于语言发展停滞在几个单词,相当一部分自闭症谱系障碍(ASD)儿童被认为是“极少言语型”。最近的进展使得可以使用自闭症诊断观察量表(ADOS)的社会情感(SA)和局限重复行为(RRB)领域严重程度评分来检查ASD症状的严重程度。本研究的目的是探讨一组在学前阶段接受评估的极少言语型自闭症儿童的语言发展结果,并确定核心领域的ASD症状严重程度是否以及如何预测5岁时口语的发展。
样本包括70名在首次评估时年龄为1至5岁的自闭症儿童,他们在至少1年后,即5岁时再次接受检查。ADOS语言项目的总体水平用于将儿童分类为极少言语型或有短语性言语,而穆伦早期学习量表用作表达性语言的连续测量指标。
在时间1时,样本中65%(n = 47)的儿童是极少言语型,到时间2时,其中36%(47名中的17名)发展出了短语性言语。虽然时间1的ADOS校准严重程度评分不能预测儿童在时间2时是否仍为极少言语型,但SA校准严重程度评分的变化(而非RRB)可预测表达性语言的连续测量指标。然而,当将非言语认知能力加入模型时,SA严重程度的变化不再能预测连续的表达性语言。
研究结果表明,SA症状的严重程度与连续的语言结果有一定关系,但与分类结果无关。然而,本研究证实了非言语认知能力的普遍影响,因为将其加入模型后,SA严重程度的预测效用失效。