Touny Ahmed, Othman Haitham, Maamoon Sherif, Ramzy Samy, Elmarakby Hamdy
Surgical Oncology Department, National Cancer Institute, Cairo University, Fom Elkhalig, Cairo, Egypt.
J Surg Oncol. 2014 Nov;110(6):752-7. doi: 10.1002/jso.23692. Epub 2014 Jun 24.
The perineal wound is a major source of morbidity after abdominoperineal resection (APR) for rectal cancer, particularly after preoperative irradiation. Myocutaneous flap reconstruction is a viable alternative to primary perineal wound repair providing well-vascularized non-irradiated tissue to fill the dead space, and improve wound healing.
Sixty patients with low rectal cancer receiving neoadjuvant radiotherapy were prospectively randomized to either primary perineal wound closure (Group B) or VRAM perineal reconstruction (Group A). The study was carried out in the surgical department, National Cancer Institute (NCI), Cairo University over a period of 4 years from August 2008 to July 2012. All patients were evaluated as regards incidence of perineal wound complications, abdominal wall complications, and added co-morbidity.
Perineal wound complications were observed in 5 patients in group A (17.2%) and in 14 patients in group B (46.4%) (P = 0.015). There was no significant difference in the incidence of abdominal wound morbidity between both groups. Operative blood loss and time were lower in group B.
The vertical rectus myocutaneous flap (VRAM) is a relatively simple and reliable technique for perineal wound reconstruction after abdominoperineal resection.
会阴伤口是直肠癌腹会阴联合切除术(APR)后发病的主要来源,尤其是在术前放疗后。肌皮瓣重建是一种可行的替代方法,可用于会阴伤口一期修复,提供血运良好的未受照射组织来填充死腔,促进伤口愈合。
60例接受新辅助放疗的低位直肠癌患者被前瞻性随机分为会阴伤口一期缝合组(B组)或腹直肌肌皮瓣(VRAM)会阴重建组(A组)。该研究于2008年8月至2012年7月在开罗大学国家癌症研究所外科进行,为期4年。对所有患者的会阴伤口并发症、腹壁并发症及额外合并症的发生率进行评估。
A组有5例患者(17.2%)出现会阴伤口并发症,B组有14例患者(46.4%)出现会阴伤口并发症(P = 0.015)。两组腹部伤口发病率无显著差异。B组手术失血量和手术时间较少。
腹直肌肌皮瓣(VRAM)是腹会阴联合切除术后会阴伤口重建的一种相对简单且可靠的技术。