Daly Adrian F, Beckers Albert
Department of EndocrinologyCentre Hospitalier Universitaire de Liège, University of Liège, Domaine Universitaire du Sart-Tilman, 4000 Liège, Belgium
Department of EndocrinologyCentre Hospitalier Universitaire de Liège, University of Liège, Domaine Universitaire du Sart-Tilman, 4000 Liège, Belgium.
Endocr Relat Cancer. 2014 Aug;21(4):C7-9. doi: 10.1530/ERC-14-0296. Epub 2014 Jun 25.
This issue analyzes new work expanding the range of how genetic dysregulation of succinate dehydrogenase subunit (SDHx) genes can cause cancer syndromes with a prominent endocrine component, in this case Carney triad, which is characterized by gastrointestinal stromal tumors, paraganglioma, and pulmonary chondromas.
本期分析了新的研究工作，这些工作拓展了琥珀酸脱氢酶亚基（SDHx）基因的遗传失调导致具有显著内分泌成分的癌症综合征的方式范围，在这种情况下是卡尼三联征，其特征为胃肠道间质瘤、副神经节瘤和肺软骨瘤。
