暴露于城市应激源的工人中镉与血细胞计数之间的相关性。
Correlation between cadmium and blood counts in workers exposed to urban stressor.
作者信息
Ciarrocca M, Rosati M V, Tomei F, Pacchiarotti A, Corbosiero P, Di Pastena C, Scala B, Capozzella A, Tomei G, Caciari T, Sacco C, Sancini A
机构信息
a Unit of Occupational Medicine, Department of Anatomy, Histology, Medical-Legal and the Orthopedics , University of Rome "Sapienza," Rome , Italy.
出版信息
Arch Environ Occup Health. 2015;70(2):70-6. doi: 10.1080/19338244.2013.778807.
The objective of this study was to assess the exposures to cadmium (Cd) in urban workers and the association between Cd exposure and values of blood counts. Urinary Cd, blood Cd, and blood counts were obtained from 355 outdoor workers; a subgroup of 99 subjects were monitored to evaluate personal exposure to airborne Cd. The mean value of personal exposure to Cd was 1.5 ng/m3 for traffic assistants and 1.2 ng/m3 for drivers. Urinary and blood Cd were correlated to the airborne Cd (respectively r=3 and r=4). The multiple linear regression models showed the associations among white blood cell, the percentage of neutrophils (NEU%), the percentage of lymphocytes (LYM%), and the concentrations of blood Cd (respectively R2=27, R2=37, R2=581). The subjects with blood Cd values higher than 1.2 μg/L showed an increase of LYM% mean values and a decrease of NEU% mean values with respect to the group with blood Cd values lower than 1.1 μg/L.
本研究的目的是评估城市工人的镉（Cd）暴露情况以及镉暴露与血细胞计数之间的关联。从355名户外工作者中获取了尿镉、血镉和血细胞计数；对99名受试者的一个亚组进行了监测，以评估其对空气中镉的个人暴露情况。交通协管员的镉个人暴露平均值为1.5 ng/m3，司机为1.2 ng/m3。尿镉和血镉与空气中的镉相关（r分别为3和4）。多元线性回归模型显示了白细胞、中性粒细胞百分比（NEU%）、淋巴细胞百分比（LYM%）与血镉浓度之间的关联（R2分别为27、37、581）。血镉值高于1.2 μg/L的受试者相对于血镉值低于1.1 μg/L的组，其LYM%平均值增加，NEU%平均值降低。
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