Malkan A D, Wahid F N, Fernandez-Pineda I, Sandoval J A
Department of Surgery, St. Jude Children's Research Hospital, MS 133, Room D3045, 262 Danny Thomas Place, Memphis, TN, 38105-3678, USA,
Clin Transl Oncol. 2015 Mar;17(3):197-200. doi: 10.1007/s12094-014-1196-4. Epub 2014 Jun 26.
The discovery of an appendiceal carcinoid tumor found incidentally or during the course of diagnostic or therapeutic procedures is a burden to both the patient and clinician. The role of the correct surgical operation is paramount for lesions suspected to be malignant. In the pediatric population, appendiceal carcinoids continue to challenge the clinician in choosing the optimal treatment when lesions are larger than 2 cm or involve the appendical base. While the criteria used to define these distinct lesions are available in most cases, the management and treatment are still debated and controversial when considering more radical surgical intervention. The purpose of this article is to give an overview regarding the history, diagnosis, histopathology, management, and controversies associated with appendiceal carcinoid in the pediatric population.
偶然发现或在诊断或治疗过程中发现阑尾类癌肿瘤,这对患者和临床医生来说都是一种负担。对于疑似恶性的病变,正确的外科手术作用至关重要。在儿科人群中,当阑尾类癌病变大于2厘米或累及阑尾根部时,在选择最佳治疗方案方面,仍然给临床医生带来挑战。虽然在大多数情况下可获得用于定义这些不同病变的标准,但在考虑更激进的外科干预时,其管理和治疗仍存在争议。本文旨在概述儿科人群中与阑尾类癌相关的病史、诊断、组织病理学、管理及争议。