Shi Hai Yun, Ng Siew C, Tsoi Kelvin K F, Wu Justin C Y, Sung Joseph J Y, Chan Francis K L
Department of Medicine and Therapeutics, Institute of Digestive Disease, Prince of Wales Hospital, Chinese University of Hong Kong, NT, HK.
Expert Rev Gastroenterol Hepatol. 2015 Jan;9(1):47-54. doi: 10.1586/17474124.2014.934359. Epub 2014 Jun 25.
Assessment of mucosal inflammation is important in the management of patients with ulcerative colitis (UC). Colon capsule endoscopy (CCE) has recently been shown to be effective in colorectal polyp detection. However, its role in the evaluation of mucosal inflammation in UC is unclear. This systematic review aims to clarify the state of the art with an evidence-based summary of current studies on the utility of CCE in UC. The overall results show that the accuracy of CCE for assessment of mucosal inflammation in UC appeared to be comparable with that of colonoscopy. Long-term follow-up studies with larger sample size are needed to further validate the utility of CCE in the management of UC subjects in clinical practice.
评估黏膜炎症在溃疡性结肠炎(UC)患者的管理中很重要。结肠胶囊内镜检查(CCE)最近已被证明在结直肠息肉检测中有效。然而,其在UC黏膜炎症评估中的作用尚不清楚。本系统评价旨在通过对CCE在UC中应用的当前研究进行循证总结来阐明现有状况。总体结果表明,CCE评估UC黏膜炎症的准确性似乎与结肠镜检查相当。需要更大样本量的长期随访研究来进一步验证CCE在临床实践中管理UC患者的效用。