• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

链霉素-利多卡因注射治疗带状疱疹后神经痛：三例报告并文献复习

Streptomycin-lidocaine injections for the treatment of postherpetic neuralgia: Report of three cases with literature review.

作者信息

Waghray Shefali, Asif Shaik Mohammed, Duddu Mahesh Kumar, Arakeri Gururaj

机构信息

Department of Oral Medicine and Radiology, Panineeya Mahavidhyalaya Institute of Dental Sciences and Research Centre, Hyderabad, Andhra Pradesh, India.

Department of Maxillo Facial Diagnostic Sciences, College of Dentistry, King Khalid University, Abha, Saudi Arabia.

出版信息

Eur J Dent. 2013 Sep;7(Suppl 1):S105-10. doi: 10.4103/1305-7456.119086.

DOI:10.4103/1305-7456.119086
PMID:24966716
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4054067/
Abstract

The sudden, stabbing, paroxysmal pain of neuralgia is the fiercest agony that a patient may experience in his life. Many varied medical treatments and surgical procedures have been suggested in the literature for neuralgic pain. Most of the patients fail to respond to medical treatments or succumb to complications of total anesthesia owing to surgical procedures. Herein, we tried a new treatment modality in patients suffering from postherpetic neuralgia with appreciable success in all the three cases that are presented in this paper. Streptomycin sulfate dissolved in 2% lidocaine solution was deposited at the peripheral branches on the involved nerves targeting the trigger zones, given weekly once for a maximum of 6 week period and continued once in 2 weeks if symptoms persisted. All patients were followed-up for 1 year and there was a marked improvement on follow-up.

摘要

神经痛突然发作的刺痛、阵发性疼痛是患者一生中可能经历的最剧烈的痛苦。文献中针对神经痛提出了许多不同的医学治疗方法和外科手术。大多数患者对医学治疗无反应，或因外科手术而死于全身麻醉的并发症。在此，我们对患有带状疱疹后神经痛的患者尝试了一种新的治疗方式，本文所呈现的3例患者均取得了显著成功。将硫酸链霉素溶解于2%利多卡因溶液中，注射到受累神经的外周分支上的触发区，每周注射1次，最多注射6周；如果症状持续，则每2周注射1次。所有患者均随访1年，随访时病情有显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d2f/4054067/b2213eb84ddd/EJD-7-105-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d2f/4054067/8ae0c0270927/EJD-7-105-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d2f/4054067/07c475559c9b/EJD-7-105-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d2f/4054067/ca4803028959/EJD-7-105-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d2f/4054067/3b5dc982ef36/EJD-7-105-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d2f/4054067/4dcdd3b14b8c/EJD-7-105-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d2f/4054067/b2213eb84ddd/EJD-7-105-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d2f/4054067/8ae0c0270927/EJD-7-105-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d2f/4054067/07c475559c9b/EJD-7-105-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d2f/4054067/ca4803028959/EJD-7-105-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d2f/4054067/3b5dc982ef36/EJD-7-105-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d2f/4054067/4dcdd3b14b8c/EJD-7-105-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d2f/4054067/b2213eb84ddd/EJD-7-105-g006.jpg

相似文献

1
Streptomycin-lidocaine injections for the treatment of postherpetic neuralgia: Report of three cases with literature review.链霉素-利多卡因注射治疗带状疱疹后神经痛：三例报告并文献复习
Eur J Dent. 2013 Sep;7(Suppl 1):S105-10. doi: 10.4103/1305-7456.119086.
2
Peripheral streptomycin/lidocaine injections in the treatment of idiopathic trigeminal neuralgia. A preliminary report.
J Maxillofac Surg. 1986 Feb;14(1):8-9. doi: 10.1016/s0301-0503(86)80249-1.
3
Intrathecal methylprednisolone for intractable postherpetic neuralgia.鞘内注射甲基强的松龙治疗顽固性带状疱疹后神经痛。
N Engl J Med. 2000 Nov 23;343(21):1514-9. doi: 10.1056/NEJM200011233432102.
4
Topical lidocaine for the treatment of postherpetic neuralgia.外用利多卡因治疗带状疱疹后神经痛。
Cochrane Database Syst Rev. 2007 Apr 18(2):CD004846. doi: 10.1002/14651858.CD004846.pub2.
5
The effects of streptomycin/lidocaine block on trigeminal neuralgia: a double blind crossover placebo controlled study.链霉素/利多卡因阻滞对三叉神经痛的影响：一项双盲交叉安慰剂对照研究。
Headache. 1993 Mar;33(3):155-60. doi: 10.1111/j.1526-4610.1993.hed3303155.x.
6
Interventional Treatments for Postherpetic Neuralgia: A Systematic Review.疱疹后神经痛的介入治疗：系统评价。
Pain Physician. 2019 May;22(3):209-228.
7
Efficacy and safety of 5% lidocaine (lignocaine) medicated plaster in comparison with pregabalin in patients with postherpetic neuralgia and diabetic polyneuropathy: interim analysis from an open-label, two-stage adaptive, randomized, controlled trial.5%利多卡因（ lignocaine ）药用贴剂与普瑞巴林治疗带状疱疹后神经痛和糖尿病性多发性神经病患者的疗效及安全性比较：一项开放标签、两阶段适应性、随机对照试验的中期分析
Clin Drug Investig. 2009;29(4):231-41. doi: 10.2165/00044011-200929040-00002.
8
Thermographic follow-up of postherpetic neuralgia (PHN) subsequent to Ramsay Hunt syndrome with multicranial nerve (V, VII, VIII and IX) involvement: a case report.Ramsay Hunt 综合征累及多颅神经（V、VII、VIII 和 IX）后继发带状疱疹后神经痛的热成像随访：病例报告。
BMC Neurol. 2021 Jan 28;21(1):39. doi: 10.1186/s12883-021-02071-5.
9
Long-term treatment of neuropathic pain with a 5% lidocaine medicated plaster.长期使用 5%利多卡因贴剂治疗神经病理性疼痛。
Eur J Anaesthesiol. 2010 Feb;27(2):169-73. doi: 10.1097/EJA.0b013e328330e989.
10
5% lidocaine medicated plaster in elderly patients with postherpetic neuralgia: results of a compassionate use programme in France.5% 利多卡因贴剂治疗老年带状疱疹后神经痛患者：法国同情用药项目的结果。
Drugs Aging. 2011 Sep 1;28(9):693-702. doi: 10.2165/11595600-000000000-00000.

引用本文的文献

1
Preparation, Characterization, and Pharmacological Activity of Cymbopogon winterianus Jowitt ex Bor (Poaceae) Leaf Essential Oil of β-Cyclodextrin Inclusion Complexes.爪哇香茅（禾本科）叶精油β-环糊精包合物的制备、表征及药理活性
Evid Based Complement Alternat Med. 2015;2015:502454. doi: 10.1155/2015/502454. Epub 2015 Jul 13.

本文引用的文献

1
Herpes zoster (shingles) and postherpetic neuralgia.带状疱疹（蛇串疮）及带状疱疹后神经痛。
Mayo Clin Proc. 2009 Mar;84(3):274-80. doi: 10.4065/84.3.274.
2
An update on the treatment of postherpetic neuralgia.带状疱疹后神经痛治疗的最新进展。
J Pain. 2008 Jan;9(1 Suppl 1):S19-30. doi: 10.1016/j.jpain.2007.10.006.
3
Botulinum toxin and intractable trigeminal neuralgia.肉毒杆菌毒素与顽固性三叉神经痛
Clin Neuropharmacol. 2005 Jul-Aug;28(4):161-2. doi: 10.1097/01.wnf.0000172497.24770.b0.
4
Pregabalin reduces pain and improves sleep and mood disturbances in patients with post-herpetic neuralgia: results of a randomised, placebo-controlled clinical trial.普瑞巴林可减轻带状疱疹后神经痛患者的疼痛，并改善睡眠和情绪障碍：一项随机、安慰剂对照临床试验的结果。
Pain. 2004 May;109(1-2):26-35. doi: 10.1016/j.pain.2004.01.001.
5
Once, twice, or three times daily famciclovir compared with aciclovir for the oral treatment of herpes zoster in immunocompetent adults: a randomized, multicenter, double-blind clinical trial.免疫功能正常的成人带状疱疹口服治疗中，每日1次、2次或3次服用泛昔洛韦与阿昔洛韦的比较：一项随机、多中心、双盲临床试验
J Clin Virol. 2004 Apr;29(4):248-53. doi: 10.1016/S1386-6532(03)00164-1.
6
[Local use of Streptmycin in the treatment of pain syndromes].
Ideggyogy Sz. 1963 May;16:145-51.
7
Herpes zoster--predicting and minimizing the impact of post-herpetic neuralgia.带状疱疹——预测并将带状疱疹后神经痛的影响降至最低
J Antimicrob Chemother. 2001 Feb;47 Suppl T1:1-8. doi: 10.1093/jac/47.suppl_1.1.
8
The lifetime occurrence of Herpes zoster and prevalence of post-herpetic neuralgia: A retrospective survey in an elderly population.带状疱疹的终生发病率及带状疱疹后神经痛的患病率：一项老年人群的回顾性调查。
Eur J Pain. 1999 Dec;3(4):335-342. doi: 10.1053/eujp.1999.0139.
9
Gabapentin for the treatment of postherpetic neuralgia: a randomized controlled trial.加巴喷丁治疗带状疱疹后神经痛：一项随机对照试验。
JAMA. 1998 Dec 2;280(21):1837-42. doi: 10.1001/jama.280.21.1837.
10
Use of streptomycin-lidocaine injections in the treatment of the cluster-tic syndrome. Clinical perspectives and a case report.链霉素-利多卡因注射剂在丛集性抽搐综合征治疗中的应用。临床观点及病例报告。
J Craniomaxillofac Surg. 1996 Oct;24(5):289-92. doi: 10.1016/s1010-5182(96)80061-8.