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脾边缘区细胞淋巴瘤(SMZL):脾脏自发性破裂表现的报告。

Splenic marginal cell lymphoma (SMZL): report of its presentation with spontaneous rupture of the spleen.

作者信息

Aldridge Malcolm C, Nederstrom Camilla, Swamy Rajiv

机构信息

East and North Herts Trust, Welwyn Garden City, Hertfordshire, UK.

East and North Herts Trust, Lister Hospital, Hertfordshire, UK

出版信息

J Surg Case Rep. 2013 Dec 16;2013(12):rjt105. doi: 10.1093/jscr/rjt105.

Abstract

Rupture of the spleen is a potentially life-threatening condition, which most often occurs secondary to abdominal trauma. Spontaneous rupture of the spleen is a much rarer event, usually occurring secondary to infections and less frequently secondary to haematological malignancies causing massive splenomegaly. We present a case of a 71-year-old woman who presented in the emergency department with acute abdominal and back pain and no history of trauma, with a CT scan diagnosis of splenic rupture. Splenectomy was performed and the histological examination of the specimen revealed splenic marginal cell lymphoma (SMZL), which is classified under the non-Hodgkins lymphomas (NHL) and accounts for <1% of NHL. There is only one previously reported case of spontaneous splenic rupture SMZL and this is the first recorded case of spontaneous splenic rupture in a patient without massive splenomegaly.

摘要

脾破裂是一种可能危及生命的病症,最常继发于腹部创伤。脾自发性破裂则更为罕见,通常继发于感染,较少继发于导致脾肿大的血液系统恶性肿瘤。我们报告一例71岁女性患者,该患者因急性腹痛和背痛就诊于急诊科,无创伤史,CT扫描诊断为脾破裂。患者接受了脾切除术,标本的组织学检查显示为脾边缘区细胞淋巴瘤(SMZL),该淋巴瘤归类于非霍奇金淋巴瘤(NHL),占NHL的比例不到1%。此前仅有一例关于SMZL自发性脾破裂的报道,而这是首例记录在案的无脾肿大患者的自发性脾破裂病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eef8/3888001/5b5fbe9e312a/rjt10501.jpg

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