Samad Irenawati, Wang Margaret Choon Lee, Chong Vui Heng
Southeast Asian J Trop Med Public Health. 2014 Mar;45(2):352-6.
Infections are a serious complication in patients with systemic lupus erythematosus (SLE), and are an important cause of morbidity and mortality. SLE patients are particularly susceptible to infection due to immune suppression from underlying disease or treatment. Most infections are due to common bacterial organisms. Clinicians also need to be aware of the possibility of polymicrobial infections as these may cause diagnostic delay and affect outcomes. We report the case of an intra-cerebral coinfection with Burkholderia pseudomallei and Cryptococcus neoformans in a 34-year-old woman with SLE. The diagnosis in this case was delayed since coinfection was not suspected.
感染是系统性红斑狼疮（SLE）患者的严重并发症，也是发病和死亡的重要原因。由于基础疾病或治疗导致的免疫抑制，SLE患者特别容易感染。大多数感染是由常见的细菌病原体引起的。临床医生还需要意识到多重微生物感染的可能性，因为这些感染可能会导致诊断延迟并影响治疗结果。我们报告了一例34岁SLE女性患者发生的脑内伯克霍尔德菌和新型隐球菌合并感染病例。由于未怀疑合并感染，该病例的诊断被延迟。
